S.Amdt. 1234Senate119th Congress (2025-2027)

S.Amdt. 1234

Submitted March 6, 2025

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Senate amendment submitted

March 6, 2025

Text

Submitted

SA 1234. Mr. BOOKER submitted an amendment intended to be proposed by
him to the bill S. 331, to amend the Controlled Substances Act with
respect to the scheduling of fentanyl-related substances, and for other
purposes; which was ordered to lie on the table; as follows:

In subsection (e) of section 202(c) of the Controlled
Substances Act (21 U.S.C. 812(c)), as added by section 2,
strike paragraph (2) and insert the following:
``(2) For purposes of paragraph (1), except as provided in
paragraph (3), the term `fentanyl-related substance' means
any substance that--
``(A) is an opioid mu receptor agonist with potential for
misuse or abuse, as demonstrated by binding studies and
functional assays; and
``(B) is structurally related to fentanyl by 1 or more of
the following modifications:
``(i) By replacement of the phenyl portion of the phenethyl
group by any monocycle,

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whether or not further substituted in or on the monocycle.
``(ii) By substitution in or on the phenethyl group with
alkyl, alkenyl, alkoxyl, hydroxyl, halo, haloalkyl, amino, or
nitro groups.
``(iii) By substitution in or on the piperidine ring with
alkyl, alkenyl, alkoxyl, ester, ether, hydroxyl, halo,
haloalkyl, amino, or nitro groups.
``(iv) By replacement of the aniline ring with any aromatic
monocycle whether or not further substituted in or on the
aromatic monocycle.
``(v) By replacement of the N-propionyl group with another
acyl group.
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