S. 4494Senate119th Congress (2025-2027)In Committee

A bill to prioritize funding for an expanded and sustained national investment in biomedical research.

Introduced May 12, 2026

AI-Generated Summary

Updated May 14, 2026 at 2:53 AM UTC

The American Cures Act directs the federal government to increase and protect funding for biomedical research. It sets specific dollar amounts for the National Institutes of Health, the Centers for Disease Control and Prevention, the Department of Defense health research program, and the Veterans Affairs medical and prosthetics research program from fiscal year 2027 through 2037, with future years adjusted for inflation. The money must be spent on research and remains available until used, and the appropriations are shielded from budget cuts under sequestration and PAYGO rules.

Key Provisions

  • Appropriates $52.5 billion for NIH in FY2027, rising each year to $102.3 billion in FY2036, with FY2037 and later amounts tied to the previous year’s CPI increase.
  • Appropriates $9.9 billion for CDC in FY2027, increasing each year to $19.3 billion in FY2036, with later years adjusted for CPI.
  • Appropriates $2.94 billion for the DoD health research, development, test, and evaluation program in FY2027, growing to $5.73 billion in FY2036, with CPI adjustments thereafter.
  • Appropriates $1.07 billion for VA medical and prosthetics research in FY2027, rising to $1.98 billion in FY2036, with future amounts indexed to CPI.
  • All appropriated funds remain available until expended.
  • The appropriations are exempt from sequestration cuts under the Balanced Budget and Emergency Deficit Control Act.
  • The funding impacts are excluded from statutory and Senate PAYGO scorecards.

Legislative Activity

Stay on top of the latest movement without scrolling through every action

1 earlier action
SenateIntro Referral Latest Action

Read twice and referred to the Committee on Appropriations. (text: CR S2239)

May 12, 2026

View full timeline
SenateIntro Referral

Introduced in Senate

May 12, 2026

SenateIntro Referral

Read twice and referred to the Committee on Appropriations. (text: CR S2239)

May 12, 2026

Floor Debate

2 members

What members said about S. 4494 on the floor

1 Republican1 Democrat
John Cornyn
Sen. John CornynR-TX · May 12, 2026

Mr. President, on another matter, I am introducing a bill called the Barring American Citizenship by Keeping Out Foreign Fraudsters or the BACK OFF Act. This bill is designed to address a problem…

Richard J. Durbin
Sen. Richard J. DurbinD-IL · May 12, 2026

Mr. President, I ask unanimous consent that the text of the bill be printed in the Record.

Richard J. Durbin
Sen. Richard J. DurbinD-IL · May 12, 2026

Mr. President, I ask unanimous consent that the text of the bill be printed in the Record.

Bill Text

Latest available legislative text

Reading Mode
Latest
Introduced in SenateIssued May 12, 2026

II

119th CONGRESS

2d Session

S. 4494

IN THE SENATE OF THE UNITED STATES

May 12, 2026

Mr. Durbin (for himself, Mr. Blumenthal, Ms. Duckworth, and Mr. Van Hollen) introduced the following bill; which was read twice and referred to the Committee on Appropriations

A BILL

To prioritize funding for an expanded and sustained national investment in biomedical research.

1.

Short title

This Act may be cited as the American Cures Act.

2.

Appropriations for Innovation

(a)

In general

There are hereby authorized to be appropriated, and appropriated, out of any monies in the Treasury not otherwise appropriated, the following:

(1)

National Institutes of Health

For the National Institutes of Health at the Department of Health and Human Services—

(A)

for fiscal year 2027, $52,467,132,000;

(B)

for fiscal year 2028, $56,507,101,164;

(C)

for fiscal year 2029, $60,858,147,954;

(D)

for fiscal year 2030, $65,544,225,346;

(E)

for fiscal year 2031, $70,591,130,698;

(F)

for fiscal year 2032, $76,026,647,762;

(G)

for fiscal year 2033, $81,880,699,640;

(H)

for fiscal year 2034, $88,185,513,512;

(I)

for fiscal year 2035, $94,975,798,052;

(J)

for fiscal year 2036, $102,288,934,502; and

(K)

for fiscal year 2037 and each fiscal year thereafter, the amount appropriated under this paragraph for the previous fiscal year, increased by the percentage increase (if any), during the previous fiscal year, in the Consumer Price Index for all urban consumers published by the Bureau of Labor Statistics.

(2)

Centers for Disease Control and Prevention

For the Centers for Disease Control and Prevention at the Department of Health and Human Services—

(A)

for fiscal year 2027,$ 9,911,621,307;

(B)

for fiscal year 2028, $10,674,816,148;

(C)

for fiscal year 2029, $11,496,776,991;

(D)

for fiscal year 2030, $12,382,028,819;

(E)

for fiscal year 2031, $13,335,445,038;

(F)

for fiscal year 2032, $14,362,274,306;

(G)

for fiscal year 2033, $15,468,169,428;

(H)

for fiscal year 2034, $16,659,218,474;

(I)

for fiscal year 2035, $17,941,978,296;

(J)

for fiscal year 2036, $19,323,510,625; and

(K)

for fiscal year 2037 and each fiscal year thereafter, the amount appropriated under this paragraph for the previous fiscal year, increased by the percentage increase (if any), during the previous fiscal year, in the Consumer Price Index for all urban consumers published by the Bureau of Labor Statistics.

(3)

Research, development, test, and evaluation program of the Department of Defense health program

For the research, development, test, and evaluation program of the Department of Defense health program—

(A)

for fiscal year 2027, $2,939,358,093;

(B)

for fiscal year 2028, $3,165,688,666;

(C)

for fiscal year 2029, $3,409,451,694;

(D)

for fiscal year 2030, $3,671,979,474;

(E)

for fiscal year 2031, $3,954,721,894;

(F)

for fiscal year 2032, $4,259,235,480;

(G)

for fiscal year 2033, $4,587,196,612;

(H)

for fiscal year 2034, $4,940,412,751;

(I)

for fiscal year 2035, $5,320,824,534;

(J)

for fiscal year 2036, $5,730,508,023; and

(K)

for fiscal year 2037 and each fiscal year thereafter, the amount appropriated under this paragraph for the previous fiscal year, increased by the percentage increase (if any), during the previous fiscal year, in the Consumer Price Index for all urban consumers published by the Bureau of Labor Statistics.

(4)

Medical and prosthetics research program of the Department of Veterans Affairs

For the medical and prosthetics research program of the Department of Veterans Affairs—

(A)

for fiscal year 2027, $1,071,765,000;

(B)

for fiscal year 2028, $1,096,132,905;

(C)

for fiscal year 2029, $1,180,535,138;

(D)

for fiscal year 2030, $1,271,436,344;

(E)

for fiscal year 2031, $1,369,336,942;

(F)

for fiscal year 2032, $1,474,775,887;

(G)

for fiscal year 2033, $1,588,333,630;

(H)

for fiscal year 2034, $1,710,636,320;

(I)

for fiscal year 2035, $1,842,355,321;

(J)

for fiscal year 2036, $1,984,218,681; and

(K)

for fiscal year 2037 and each fiscal year thereafter, the amount appropriated under this paragraph for the previous fiscal year, increased by the percentage increase (if any), during the previous fiscal year, in the Consumer Price Index for all urban consumers published by the Bureau of Labor Statistics.

(b)

Availability

Amounts appropriated under subsection (a) shall remain available until expended.

(c)

Definitions

In this section:

(1)

Centers for Disease Control and Prevention

The term Centers for Disease Control and Prevention means the appropriations accounts that support the various institutes, offices, and centers that make up the Centers for Disease Control and Prevention.

(2)

Research, development, test, and evaluation program of the Department of Defense health program

The term research, development, test, and evaluation program of the Department of Defense health program means the appropriations accounts that support the various institutes, offices, and centers that make up the research, development, test, and evaluation program of the Department of Defense health program.

(3)

Medical and prosthetics research program of the Department of Veterans Affairs

The term medical and prosthetics research program of the Department of Veterans Affairs means the appropriations accounts that support the various institutes, offices, and centers that make up the medical and prosthetics research program of the Department of Veterans Affairs.

(4)

National Institutes of Health

The term National Institutes of Health means the appropriations accounts that support the various institutes, offices, and centers that make up the National Institutes of Health.

(d)

Exemption of certain appropriations from sequestration

(1)

In general

Section 255(g)(1)(A) of the Balanced Budget and Emergency Deficit Control Act (2 U.S.C. 905(g)(1)(A)) is amended by inserting after Advances to the Unemployment Trust Fund and Other Funds (16–0327–0–1–600). the following:

Appropriations under the American Cures Act.

.

(2)

Applicability

The amendment made by this section shall apply to any sequestration order issued under the Balanced Budget and Emergency Deficit Control Act of 1985 (2 U.S.C. 900 et seq.) on or after the date of enactment of this Act.

(e)

Budgetary effects

(1)

Statutory paygo scorecards

The budgetary effects of this section shall not be entered on either PAYGO scorecard maintained pursuant to section 4(d) of the Statutory Pay-As-You-Go Act of 2010 (2 U.S.C. 933(d)).

(2)

Senate paygo scorecards

The budgetary effects of this section shall not be entered on any PAYGO scorecard maintained for purposes of section 4106 of H. Con. Res. 71 (115th Congress).