H.R. 1266House119th Congress (2025-2027)Passed House

Combating Illicit Xylazine Act

Introduced February 12, 2025

AI-Generated Summary

Updated September 22, 2026 at 5:43 AM UTC

The Combating Illicit Xylazine Act makes the drug xylazine a Schedule III controlled substance and limits its legal use to veterinary and certain animal‑related purposes. It creates new definitions, sets up reporting requirements, and directs the Sentencing Commission to adjust penalties for illegal xylazine activity. The bill mainly affects veterinarians, pharmacies that dispense veterinary prescriptions, animal‑care facilities, and manufacturers of xylazine.

Key Provisions

  • Defines “xylazine” and adds it to the Controlled Substances Act’s Schedule III.
  • Specifies that only veterinarians or pharmacies with a veterinary prescription may dispense xylazine, and only for animals owned by the user, animals under the user’s care, government animal‑control programs, or wildlife programs.
  • Delays the start of labeling, packaging, practitioner registration, inventory, and record‑keeping requirements for xylazine (labeling delayed 1 year, registration delayed 60 days).
  • Exempts manufacturers from having to install Schedule III security standards for xylazine production at the time of enactment.
  • Requires the DEA and FDA to speed up the transition of xylazine to Schedule III and adds xylazine to the ARCOS tracking system.
  • Directs the U.S. Sentencing Commission to review and, if needed, revise sentencing guidelines for offenses involving xylazine.
  • Mandates the Attorney General (through DEA and FDA) to submit an initial report within 18 months and a follow‑up report within 4 years on the prevalence, sources, and trafficking of illicit xylazine.

Legislative Activity

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17 earlier actions
SenateCalendars Latest Action

Received in the Senate. Read twice. Placed on Senate Legislative Calendar under General Orders. Calendar No. 623.

September 16, 2026

View full timeline
HouseIntro Referral

Introduced in House

February 12, 2025

HouseIntro Referral

Referred to the Committee on Energy and Commerce, and in addition to the Committee on the Judiciary, for a period to be subsequently determined by the Speaker, in each case for consideration of such provisions as fall within the jurisdiction of the committee concerned.

February 12, 2025

HouseCommittee

Referred to the Subcommittee on Health.

February 12, 2025

HouseCommittee

Subcommittee Consideration and Mark-up Session Held

June 25, 2026

HouseCommittee

Forwarded by Subcommittee to Full Committee by Voice Vote.

June 25, 2026

HouseCommittee

Committee Consideration and Mark-up Session Held

July 20, 2026

HouseCommittee

Committee Consideration and Mark-up Session Held

July 21, 2026

HouseCommittee

Ordered to be Reported in the Nature of a Substitute by the Yeas and Nays: 48 - 0.

July 21, 2026

HouseCommittee

Reported (Amended) by the Committee on Energy and Commerce. H. Rept. 119-816, Part I.

September 14, 2026

HouseCommittee

Committee on the Judiciary discharged.

September 14, 2026

HouseCalendars

Placed on the Union Calendar, Calendar No. 715.

September 14, 2026

HouseFloor

Mr. Guthrie moved to suspend the rules and pass the bill, as amended.

September 15, 2026 • 7:13 PM

HouseFloor

Considered under suspension of the rules. (consideration: CR H5671-5673)

September 15, 2026 • 7:14 PM

HouseFloor

DEBATE - The House proceeded with forty minutes of debate on H.R. 1266.

September 15, 2026 • 7:14 PM

HouseFloor

Passed/agreed to in House: On motion to suspend the rules and pass the bill, as amended Agreed to by voice vote.

September 15, 2026 • 7:24 PM

HouseFloor

On motion to suspend the rules and pass the bill, as amended Agreed to by voice vote. (text: CR H5671-5672)

September 15, 2026 • 7:24 PM

HouseFloor

Motion to reconsider laid on the table Agreed to without objection.

September 15, 2026 • 7:24 PM

SenateCalendars

Received in the Senate. Read twice. Placed on Senate Legislative Calendar under General Orders. Calendar No. 623.

September 16, 2026

Floor Debate

3 members

What members said about H.R. 1266 on the floor

1 Republican2 Democrats
Jimmy Panetta
Rep. Jimmy PanettaD-CA-19 · Sep 15, 2026

Mr. Speaker, I thank the ranking member for yielding me time, and I thank Chairman Guthrie and Ranking Member Pallone for their work on this bill. Mr. Speaker, I rise in support of H.R. 1266, my…

Lizzie Fletcher
Rep. Lizzie FletcherD-TX-7 · Sep 15, 2026

Mr. Speaker, I yield myself such time as I may consume. Mr. Speaker, I rise to speak in support of H.R. 1266. This legislation classifies xylazine as a schedule III controlled substance while…

Brett Guthrie
Rep. Brett GuthrieR-KY-2 · Sep 15, 2026

Mr. Speaker, I move to suspend the rules and pass the bill (H.R. 1266) to prohibit certain uses of xylazine, and for other purposes, as amended. Mr. Speaker, I ask unanimous consent that all Members…

Bill Text

4 versions available

Reading Mode
Latest
Placed on Calendar SenateIssued September 16, 2026

II

Calendar No. 623

119th CONGRESS

2d Session

H. R. 1266

IN THE SENATE OF THE UNITED STATES

September 16, 2026

Received; read twice and placed on the calendar

AN ACT

To prohibit certain uses of xylazine, and for other purposes.

1.

Short title

This Act may be cited as the Combating Illicit Xylazine Act.

2.

Definitions

(a)

In general

In this Act, the term xylazine has the meaning given the term in paragraph (61) of section 102 of the Controlled Substances Act, as added by subsection (b) of this section.

(b)

Controlled substances act

Section 102 of the Controlled Substances Act (21 U.S.C. 802) is amended by adding at the end the following:

(61)

The term xylazine means the substance xylazine, including its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible.

.

3.

Adding xylazine to schedule III

Schedule III of section 202(c) of the Controlled Substances Act (21 U.S.C. 812) is amended by adding at the end the following:

(f)

Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of xylazine.

.

4.

Amendments

(a)

Amendment

Section 102 of the Controlled Substances Act (21 U.S.C. 802) is amended by striking paragraph (27) and inserting the following:

(27)
(A)

Except as provided in subparagraph (B), the term ultimate user means a person who has lawfully obtained, and who possesses, a controlled substance for the use by the person or for the use of a member of the household of the person or for an animal owned by the person or by a member of the household of the person.

(B)
(i)

In the case of xylazine, other than for a drug product approved under subsection (b) or (j) of section 505 of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 355), the term ultimate user means a person—

(I)

to whom xylazine was dispensed by—

(aa)

a veterinarian registered under this Act; or

(bb)

a pharmacy registered under this Act pursuant to a prescription of a veterinarian registered under this Act; and

(II)

who possesses xylazine for—

(aa)

an animal owned by the person or by a member of the household of the person;

(bb)

an animal under the care of the person;

(cc)

use in government animal-control programs authorized under applicable Federal, State, Tribal, or local law; or

(dd)

use in wildlife programs authorized under applicable Federal, State, Tribal, or local law.

(ii)

In this subparagraph, the term person includes—

(I)

a government agency or business where animals are located; and

(II)

an employee or agent of an agency or business acting within the scope of their employment or agency.

.

(b)

Facilities

An entity that manufactures xylazine, as of the date of enactment of this Act, shall not be required to make capital expenditures necessary to install the security standard required of schedule III of the Controlled Substances Act (21 U.S.C. 801 et seq.) for the purposes of manufacturing xylazine.

(c)

Labeling

The requirements related to labeling, packaging, and distribution logistics of a controlled substance in schedule III of section 202(c) of the Controlled Substances Act (21 U.S.C. 812(c)) shall not take effect for xylazine until the date that is 1 year after the date of enactment of this Act.

(d)

Practitioner registration

The requirements related to practitioner registration, inventory, and recordkeeping of a controlled substance in schedule III of section 202(c) of the Controlled Substances Act (21 U.S.C. 812(c)) shall not take effect for xylazine until the date that is 60 days after the date of enactment of this Act. A practitioner that has applied for registration during the 60-day period beginning on the date of enactment of this Act may continue their lawful activities until such application is approved or denied.

(e)

Manufacturer transition

The Food and Drug Administration and the Drug Enforcement Administration shall facilitate and expedite the relevant manufacturer submissions or applications required by the placement of xylazine on schedule III of section 202(c) of the Controlled Substances Act (21 U.S.C. 812(c)).

(f)

Clarification

Nothing in this Act, or the amendments made by this Act, shall be construed to require the registration of an ultimate user of xylazine under the Controlled Substances Act (21 U.S.C. 801 et seq.) in order to possess xylazine in accordance with subparagraph (B) of section 102(27) of that Act (21 U.S.C. 802(27)), as added by subsection (a) of this section.

5.

Arcos tracking

Section 307(i) of the Controlled Substances Act (21 U.S.C. 827(i)) is amended—

(1)

in the matter preceding paragraph (1)—

(A)

by inserting or xylazine after gamma hydroxybutyric acid;

(B)

by inserting or 512 after section 505; and

(C)

by inserting respectively, after the Federal Food, Drug, and Cosmetic Act,; and

(2)

in paragraph (6), by inserting or xylazine after gamma hydroxybutyric acid.

6.

Sentencing Commission

Pursuant to its authority under section 994(p) of title 28, United States Code, the United States Sentencing Commission shall review and, if appropriate, amend its sentencing guidelines, policy statements, and official commentary applicable to persons convicted of an offense under section 401 of the Controlled Substances Act (21 U.S.C. 841) or section 1010 of the Controlled Substances Import and Export Act (21 U.S.C. 960) to provide appropriate penalties for offenses involving xylazine that are consistent with the amendments made by this Act. In carrying out this section, the Commission should consider the common forms of xylazine as well as its use alongside other scheduled substances.

7.

Report to Congress on xylazine

(a)

Initial report

Not later than 18 months after the date of the enactment of this Act, the Attorney General, acting through the Administrator of the Drug Enforcement Administration and in coordination with the Commissioner of Food and Drugs, shall submit to Congress a report on the prevalence of illicit use of xylazine in the United States and the impacts of such use, including—

(1)

where the drug is being diverted;

(2)

where the drug is originating; and

(3)

whether any analogues to xylazine, or related or derivative substances, exist and present a substantial risk of abuse.

(b)

Additional report

Not later than 4 years after the date of the enactment of this Act, the Attorney General, acting through the Administrator of the Drug Enforcement Administration and in coordination with the Commissioner of Food and Drugs, shall submit to Congress a report updating Congress on the prevalence and proliferation of xylazine trafficking and misuse in the United States.

Passed the House of Representatives September 15, 2026.

Kevin F. McCumber,

Clerk.

September 16, 2026

Received; read twice and placed on the calendar