Mr. President, first, I congratulate Senator Specter on an exemplary opening statement on this 2-day debate we will be engaged in and also thank him, as I will in my formal statement, for his leadership over the past several years on so…
Mr. President, first, I congratulate Senator Specter on an exemplary opening statement on this 2-day debate we will be engaged in and also thank him, as I will in my formal statement, for his leadership over the past several years on so many issues of health care, and this one in particular. I am proud to join him in this effort, as I have for the last year, to try to get H.R. 810 to come up.
Mr. President, we have waited a long time for this day to come, I think too long. We could have and should have voted on H.R. 810 more than a year ago after it passed in the House with a strong bipartisan majority. So we have lost some valuable time. But more to the point, America's best medical researchers have lost valuable time. But be that as it may, H.R. 810 has finally come to the Senate floor, and we will vote on it tomorrow afternoon.
I thank majority leader Bill Frist for brokering the agreement to make this vote possible. It took courage for him to announce last summer that he supports the bill. And it took courage for him to schedule this vote. I have already commended him privately, and I commend him publicly as well.
Again, I thank Senator Specter for leading the effort to promote stem cell research for so many years. He chaired the very first hearing in Congress on embryonic stem cells, as he said in his remarks, in December of 1998. And, again, just repeating what Senator Specter had said--but for the sake of emphasis--our Labor, Health, and Human Services Appropriations Subcommittee has held 18 hearings on this research since then.
Senator Specter and I also introduced the very first bill in Congress on stem cell research in January of 2000. So Senator Specter and I have traveled a long road together, and I thank him for being such an extraordinary leader and partner in this effort.
I also thank the other Senate leaders on stem cell research: Senator Hatch, Senator Feinstein, Senator Smith, and Senator Kennedy. Counting Senator Specter and myself, there are three Republicans and three Democrats on the list who have led the effort to bring up H.R. 810 and pass it, and it has been a truly bipartisan effort all the way.
Most of all, I thank the hundreds of thousands of families and patients who never gave up, who kept up the pressure to bring this bill to the floor, and who are so eager to see H.R. 810 sent to the President's desk for his signature. They have kept the faith. Now it is our job to see they are not disappointed.
Under the UC agreement, we will debate and vote on three bills. But make no mistake, the only one that really matters is H.R. 810, the Stem Cell Research Enhancement Act. This is the one bill that, at long last, will unleash some of the most exciting and promising research of modern times.
So, as we begin this debate, it is a good time to step back and ask: Why is there so much support for H.R. 810? Hundreds of patient advocacy groups have endorsed the bill; so have dozens of Nobel Prize winning scientists, dozens of research universities, and, I might add, so has the American public. Polls now show that 72 percent of Americans support embryonic stem cell research--72 percent--compared with 24 percent who oppose it. That is a 3-to-1 margin. So the American people--three out of four--are in favor of embryonic stem cell research.
Why? Well, the answer is very simple. Embryonic stem cell research offers real hope--real hope--for people with Lou Gehrig's disease, real hope for people with Parkinson's, real hope for people with spinal cord injuries, real hope for people with heart disease, real hope for people with diabetes, real hope for people with cancer, real hope for people who suffer from autoimmune diseases such as lupus. All told, more than 100 million Americans have diseases that one day could be treated or cured with embryonic stem cell research. Here is just a brief list of them: cardiovascular disease, autoimmune disease, Alzheimer's, Parkinson's, spinal cord injuries, birth defects, severe burns-- millions of Americans who could be cured or helped with stem cell research.
But it is not just Members of Congress who are saying it; we have asked top scientists. Senator Specter and I sent letters to the National Institutes of Health last week. Senator Specter referred to that in his remarks. We asked their top scientists for their thoughts on stem cell research. Every single one of them said embryonic stem cell research offers enormous potential. We asked 19 NIH scientists-- heads of the different individual institutes--and all 19 agreed.
Here is what Dr. Zerhouni, the NIH director, wrote to us:
Embryonic stem cell research holds great promise for
treating, curing, and improving our understanding of disease.
This is from Dr. Elizabeth Nabel, the director of the Heart, Lung, and Blood Institute. She wrote:
Embryonic stem cell research has vast potential for
addressing critical health [care] needs.
And it is not just NIH scientists who believe this way. In a letter from Dr. J. Michael Bishop, who won the Nobel Prize in medicine in 1989, he writes:
The vast majority of the biomedical research community
believes that human embryonic stem cells are likely to be the
source of key discoveries related to many debilitating
diseases.
I could go on and on, but I think you get the picture. Scientists agree: embryonic stem cell research offers enormous hope--real hope-- for easing human suffering.
Now, some may ask: I thought the Federal Government already supports embryonic stem cell research. What about the speech the President gave 5 years ago?
Well, let me try to explain the President's policy as was enunciated 5 years ago. He gave the speech on August 9, 2001. I remember it well. I was listening to it. I was on the road. I was listening to it on the radio.
The President, at that time, said that federally funded scientists could conduct research on embryonic stem cells only if the stem cells had been derived prior to 9 p.m., August 9, 2001. Well, I thought to myself at the time--and I have thought since--that is rather odd. It is morally OK to do research on stem cells derived before 9 p.m., but it is not morally acceptable to do research on stem cells derived after 9 p.m.? Well, I thought to myself, why not 9:05? What about 9:15 p.m. or 9:30 or midnight? Why was 9 p.m. the magic cutoff hour on August 9, 2001?
Well, clearly it was totally arbitrary. That just happened to be when the President gave his speech. But for whatever reason, the President said only those lines derived by 9 p.m. August 9, 2001, were eligible for federally funded research.
At the time, after I checked into it, some of us were hopeful that the policy would work. But it has not, and here is why. When President Bush announced his policy, he said 78 stem cell lines were available. Many people thought 78 stem cell lines might be enough, might have enough genetic diversity to actually do the kind of research we needed. But as the years progressed, we found that only 21--only 21--of the approved lines are actually available for study; not 78, only 21.
We found out something else I did not know at the time. All 21 of these lines are contaminated by mouse cells. In other words, the embryonic stem cells were grown on mouse cells, so they are contaminated, making it highly unlikely ever to be used for any kind of human therapy. I ask: Would any of you want to have stem cells used for your illness if they were contaminated with mouse cells? I do not think so, and neither do the scientists. And the other thing we found out is that now many of the 21 lines are too unhealthy to use. They have actually become sick.
Dr. Nabel of the NIH Heart, Lung, and Blood Institute wrote to me that only four of these lines are in common use--four. Dr. Jeremy Berg, another NIH director, director of the general medical sciences, said there are about six lines in common use.
So what is happening now is that these policy restrictions are making our scientists work with one arm tied behind their back. It is having a chilling impact on scientists thinking about entering the field.
Dr. Nora Volkow, director of the NIH Drug Abuse Institute, said it is stifling interest in research. She said:
Despite general interest and enthusiasm in the scientific
community for embryonic stem cell research, the limited
number of available lines has translated into a general lack
of research proposals.
Well, if you are a research scientist at one of our hundreds of universities around the country, and you are eligible for NIH funding, would you want to do research on only four lines that may not lead to anything? Would you put in a proposal to do that? You could be one of our budding genius researchers. You might want to put your efforts and endeavors into something else rather than a dead-end policy.
So I submit that the President's policy is not a way forward, it is a dead-end street. It offers only false hope--false hope; not real hope, false hope--to the millions of people across America and the world who are suffering from diseases that could be cured or treated through embryonic stem cell research.
Meanwhile, hundreds of new stem cell lines have been derived since the President's arbitrary deadline of August 9, 2001. These lines are uncontaminated. They are healthy. But they are totally off limits to federally funded scientists. I do not mean just scientists who work at NIH; I am talking about all the scientists who work in all of our universities and research institutions across America. They are off limits--off limits. They cannot use it. It is really a shame.
I was listening to Senator Specter earlier talk about some of the earlier pronouncements, some by the Catholic Church, back in the Middle Ages, some by--he mentioned another Calvinist Church--I don't know who all he mentioned--but the views at that time and how we look back and say: How could they have been so blind to prohibit certain activities, such as using cadavers for scientific experimentation to learn how the body works so we could perhaps cure illnesses and diseases?
I was listening to that, and I thought: We have new stem cell lines, uncontaminated with mouse feeder cells, healthy, ready to go. Scientists cannot use them. And I thought: We do not require astronomers today to explore the skies with 19th century telescopes. We do not tell our geologists to study the Earth with a tape measure. If we are serious about realizing the promise of stem cell research, our scientists need access to the best stem cell lines available.
And, again, I would not want anyone to take just my word for it. I think Dr. James Battey knows more about stem cell research than anyone at the National Institutes of Health. He runs the stem cell task force there, and this is what he wrote when I asked him whether it would help our scientists to have access to more stem cell lines. Here is his direct quote:
The more cell lines available for study, the more likely a
cell line will be maximally useful for a given research, and
potentially clinical, application. For this reason, the
scientific community would be best served by having a greater
number of human embryonic stem cell lines available for
study.
That is from a letter to me from Dr. James Battey, chair of the NIH Stem Cell Task Force, dated July 13, 2006.
Dr. Volkow of the Drug Abuse Institute was even more blunt. She wrote:
Access to a wider array of embryonic stem cell lines would
definitely increase scientific opportunity and the chances of
breakthrough discoveries.
I should note that scientists in many other countries around the world do not face these kinds of arbitrary restrictions. When you talk to researchers in England, for example, our policy makes no sense to them. They cannot understand why stem cell lines derived on one date are fine to use, but if they are derived on another date they are off limits. They do not have arbitrary barriers like that in England, and that is a big reason so many of the major advances in stem cell research are happening there rather than in the United States.
So we need a stem cell policy in this country that offers real, meaningful hope to patients and their loved ones. That is what H.R. 810 would provide.
Under this bill, federally funded researchers could study any stem cell line regardless of the date it was derived as long as strict ethical guidelines are met. I think it is important to run through some of those ethical guidelines.
First, the only way a stem cell line could be eligible for federally funded research is if it were derived from an embryo that was otherwise going to be discarded. As Senator Specter pointed out, there are more than 400,000 embryos in the United States left over from fertility treatments that are currently sitting frozen in storage. The moms and dads have had all the children they want; they no longer need any more of these embryos, and most of them will be discarded. It happens every single day at fertility clinics around the country. People have used in vitro fertilization, had their children, and they don't want any more. Rather than continue to pay the facility to store them and freeze them, they call up and say we don't want them anymore. The facility discards them. It happens every day.
All we are saying is, instead of discarding them as leftover embryos, let's allow couples, if they wish, to donate them to create stem cell lines that can cure diseases and save lives. The choice is this: Throw them away or use them to ease suffering and, hopefully, cure diseases.
It is the second choice that I believe is truly moral and truly respectful of human life. Again, I have to emphasize, as I will today and tomorrow time and time again, H.R. 810 does not create any new embryos. Not one new embryo will be created under H.R. 810--only
those left over in in vitro fertilization clinics, and only if the moms and dads give their written consent.
As I said, the second ethical requirement requires them to provide informed written consent. Again, a lot of people don't realize this, but the President's policy is a little fuzzy on the matter of informed and written consent. Some of the 21 federally approved lines-- especially those coming from other countries--don't meet that requirement. So we need to pass H.R. 810 to tighten the ethical guidelines on stem cell research, so there is no question that the embryos were donated voluntarily.
Finally, H.R. 810 prohibits anyone from being paid to donate embryos. There is no chance under this bill that women could be exploited to go through the donation process against their will. So no money can change hands. The three ethical guidelines, to repeat, are: One, we can only use excess embryos in in vitro fertilization clinics; second, there must be informed written consent for the donation of those embryos; and third, no money can exchange hands to pay for any of these.
Let me address one more issue, and that is the matter of the so- called alternative ways of deriving stem cells. Some opponents of this will speak today and tomorrow and argue that we don't need to pass H.R. 810. Instead, they say, we should put our current stem cell research on hold in hopes that some new way of deriving stem cells will pan out some time, hopefully, in the future.
That would be a tragic mistake. I support any ethical means to improve the lives of human beings who are suffering. In fact, Senator Specter and I included language in our appropriations bill last year urging NIH to support research on alternative ways of deriving stem cells. But not one of these so-called alternative methods has ever succeeded in producing a stem cell line. Right now, they are just theories. Maybe one day, 5 years or 7 years or 10 years or 15 years from now, one of these methods will pan out. But maybe not.
I think this chart tells the story. The NIH estimates that there are about 400 stem cell lines worldwide, almost all of which were derived after the President's arbitrary cutoff date of August 9, 2001. Every one of these lines was derived the same way, using embryos that were left over from infertility treatments that would otherwise have been discarded. So you see on the chart ``stem cell lines derived using current method,'' and we have about 400 stem cell lines worldwide. Now, how many lines were derived using unproven alternative methods? Zero. It is 400 to zero.
Yet we will hear today and, I think, tomorrow from some who say we should pass other bills. We should not use the proven method we have, but we should go to alternative methodologies. We know right now that zero stem cell lines have been derived from using those alternative methodologies.
Again, should we pursue these alternative methods? Of course. This is no prohibition against that. We should open every door we can in the ethical pursuit to cures. But meanwhile, people we love are dying from Parkinson's and ALS, and children are suffering from juvenile diabetes. Should we say wait another 5, 7, or 10 years and see if we can derive stem cells from these alternative methods? Maybe we can, maybe we cannot. If we cannot, what do we do then? Say the doors are all closed? Meanwhile, we have many stem cell lines derived from leftover embryos in in vitro fertilization clinics.
Another point about the alternatives bill. Even if Congress were to pass it and the President signs it, it has absolutely no impact on the progress of stem cell research. That is because the other bills we are voting on here don't authorize anything NIH cannot do already. We had a hearing. Senator Santorum, the author of that bill, was at the hearing. We had people from NIH. Senator Durbin was there and he asked the question:
Can you tell me whether S. 2754--
which is another one of the companion bills we will be voting on tomorrow--
authorizes research on stem cells at the NIH that currently
is not permissible or legal?
Dr. James F. Battey at NIH said:
No, it does not.
That was on June 27 of this year. So the alternatives bill, S. 2754, might not do any harm, but it doesn't do any good either. It just says, NIH, you can do what you can already do. Well, that is fine with me; I have no problem with that. But don't be fooled into thinking that S. 2754 somehow takes the place of H.R. 810. It doesn't.
That is one more reason we need to focus on H.R. 810.
In closing, my nephew Kelly is one of the millions of Americans whose hopes depend on stem cell research. He has been a quadriplegic for about 27 years since suffering a spinal cord injury in a terrible accident while he was in the U.S. Navy and serving on an aircraft carrier. Kelly's hope has been that sometime scientists will finally find a way to mend his spinal cord so he can walk again. He has been following very closely the whole issue of embryonic stem cell research. His hope, like the hope of Christopher Reeve's, was--we all remember him, our first ``Superman''; he fought so hard for embryonic stem cell research before he passed away. They both hoped embryonic stem cell research would lead to a breakthrough that would allow them to walk again. Kelly asks all the time: When is the Senate going to vote on
Mr. President, my time is up. Again, this is going to be a good debate, a good airing of the issues. Tomorrow we will vote on this bill and send it to the President. I am hopeful that the President, after reviewing it and looking at what happened in the past--the new things that have come to light because of the mouse feeder cells and the contamination of those lines--will sign the bill and give real hope to millions of Americans.
I yield the floor.
Exhibit 1
The Amyotrophic Lateral
Sclerosis Association,
Washington, DC, July 12, 2006.
U.S. Senate,
Washington, DC.
Dear Senators: The ALS Association (ALSA) strongly supports
the Senate's consideration of legislation to advance stem
cell research. We are grateful for the bipartisan efforts of
Senators to bring this important issue up for a vote before
the August Congressional recess and are particularly
appreciative of the leadership on this issue demonstrated by
Majority Leader Bill Frist (R-TN) and Senator Tom Harkin (D-
Mr. President, I have a letter from a number of different groups endorsing H.R. 810. It is patient advocacy groups, health organizations, research universities, scientific institutes, religious groups, and others. There are 205 groups listed here. I will not go through all of them, obviously, but I think it is important that all of these groups be laid upon the Record. I ask unanimous consent that the letter be printed in the Record.
Mr. President, I have a letter from the American Society for Cell Biology. The letter was sent to Senator Hatch, dated July 17. It says:
The Senate will shortly be considering legislation to
permit the National Institutes of Health (NIH) to fund
research with additional and new and existing human embryonic
stem cell (hESC) lines. As staunch supporters of biomedical
research and particularly research with hESCs, we trust that
you will exert your influence to ensure passage of H.R. 810.
Scientists engaged in ESC research are counting on you and
like-minded Senate colleagues to assure its passage.
The President must also be persuaded not veto this
legislation for if we continue on the path he set five years
ago, United States investigators will be out of the running
in coverting embryonic stem cells into important new
therapies. It is especially frustrating and demeaning that
American scientists are prohibited from using their NIH grant
funds for research with the hundreds of hESC lines generated
outside the United States or generated in this country with
private funding.
I note there are 27 leading scientists on this letter, 17 of them having received the Nobel Prize for medicine in one form or another.
I ask unanimous consent that this letter be printed in the Record.
Yes.
I am not intimately knowledgeable of all of the nuances in research that is being done. We had hearings, and we have the information in our hearing record on a lot of that. Standing here now, I don't know all of that.
Will the Senator repeat that? I was reading something.
Let me respond this way: First, I note that the Juvenile Diabetes Research Foundation, which represents families all over America who are affected with juvenile diabetes, is in support of H.R. 810. I want that on the record. In fact, they have been one of the strongest supporters.
Second, the transplantation of insulin-producing pancreatic cells is already known to reverse the most damaging symptoms of type 1 diabetes. The problem with that is the limited number of organ donors out there who donate pancreases. That seems to be the problem.
Could I ask the Senator, are there enough pancreas donors out there to take care of everyone with juvenile diabetes?
I have heard this argument before. I am not a scientist. I don't know all of the nuances, I would be the first to admit. I do know, however, that every time that has come up, the Juvenile Diabetes Research Association disagrees that this is a viable pathway toward curing all of those with juvenile diabetes.
How many people have been cured of juvenile diabetes with this?
Is it not being done in the United States?
Have any of these findings been published?
I would appreciate that.
I thank the Senator. There is a good colloquy.
I would further ask the Senator from Oklahoma--this has been done for 3 months--do we have any data to show that this does cure juvenile diabetes? Does it abate it somewhat? I don't know what the outcomes have been for these eight or nine people.
I thank the Senator.
I again say that all the Nobel scientists, all of the leading scientists in America simply do not agree with the Senator from Oklahoma. These are the people involved in cell biology and that kind of research.
The Senator says embryonic stem cells will produce tumors. We do not know that is true. We do not have any real long-term data to know anything about how embryonic stem cells will work later on.
Mr. President, I know that one of the cosponsors of the bill, one of the great leaders in the Senate on stem cell research, has arrived on the floor to speak. I know the Chair will be recognizing her shortly.
I wanted, again, to just take a moment to sort of repeat for emphasis sake what has been said before. I think the distinguished majority leader referred to that also. It is just that here we have an instance where so many leading scientists around, U.S. Nobel Prize winners, and all the disease groups--I submitted a compendium of about 205, and I think that may soar to 500 or 600 by the end of the day--are supporting
Mr. President, I was going to ask the Senator from Kansas--I will even do it on my time. I guess our next speaker is not here right now. If the Senator from Kansas would perhaps engage me in a colloquy, I would ask about the gentleman whose picture he has up there. How is he doing now? I understand that, frankly, while his Parkinson's was relieved for a while, it has reverted and he is back in his previous state. Does the Senator know about that?
I say to my friend, I don't understand that. I have a chart here that shows stem cell funding, embryonic stem cell funding, is $38.3 million last year and adult stem cell funding is $200 million. You are telling me out of $200 million they can't help one individual?
Plus, I ask my friend from Kansas, if this is so promising, why is the entire Parkinson's network that represents all the people with Parkinson's disease 100 percent behind H.R. 810? Why are they so supportive of H.R. 810 and not this approach?
I say to my friend from Kansas--and I see Senator Nelson is here to speak. He had previously been
scheduled to do so--first, I didn't see all the figures the Senator sent to the desk. I would like to see those. I heard him talk about a half billion dollars. Frankly, what the Senator from Kansas is talking about is animal embryonic. We are talking about human--human experiments here, not animal.
I am more interested in the human than I am about human and animal.
Second, on cancer and tumors, it is my understanding--I am not a scientist, but in talking with the scientists--the fact that an undifferentiated stem cell causes cancer is exactly what they are looking for. It is the gold standard. I thought it was the gold standard for determining whether you have an embryonic stem cell.
Let me see if I can repeat it as told to me. If you derive a stem cell line from an embryo, you don't really know if you have stem cells. So the scientists take the undifferentiated cells and put them in a mouse to see if it causes cancer. That is the gold standard--to see whether there is a stem cell line.
No one is talking about putting undifferentiated cells into your body or mine or anyone else's. We are talking about undifferentiated cells and then finding how they make nerve cells, how they make heart cells, how they make tissue cells, how they make brain cells. Only after they are differentiated would they then be put into a person, not undifferentiated.
I hear all about the terms. I heard that earlier this morning. I thought I would check up on it. That is what I found out.
I would be glad to engage in a colloquy.
They are tumors. That is what I heard the Senator say.
I don't know. I am a little confused. Is the Senator saying, if a stem cell has been introduced and is undifferentiated, it causes cancer or teratoma?
But the fact is the inference from some of the statements, I think, is that thus far stem cells, when introduced, cause cancer. That is not so. That has not been proven. That has not been proven at all.
Tumors but not cancer.
We have gone down a lot of blind alleys in medical research in the past. I have often said that one of the reasons for basic research is that you have 11 doors that are closed. The answer to the problem and the answer to your endeavor may be behind one of those doors. When you have enough funding to open one door, you know what the odds are against you finding it. Or if you have funding for half, then you know what the odds are against you opening the right door. A lot of doors don't lead to anything. A lot of basic research goes down the path, and they find out that is not the answer. So they have to shift to something else. That happens all the time. That is what basic research is all about.
I do not know the specific thing. I am not surprised that many things in the past that scientists have gone down the road on have not led to something curative or therapeutic or something like that which helps us.
That doesn't mean that we have tried something before with devastating effects which doesn't say that we can't then do embryonic stem cell research.
I get back to the point that when you have almost every disease group in this country supporting the bill that is before us, H.R. 810, you have Nobel laureates, scientists, doctors, and you have 19 Directors of NIH saying that thi has great potential, then I say, again, to my friends that you have to make either one of two assumptions. Either all of these people have been hoodwinked and they do not know what they are talking about or they have no care or concern about ethics or morals or anything else. I think both assumptions are wrong. I think these people know. They are informed. They may not know every little thing medical doctors might know, but they know the potential.
Second, I think they are vastly ethical and moral people.
I hope we will have some further colloquies on this later.
The Senator has been very kind. I think we can engage at some other point.
I yield the floor.
How much time remains on our side?
Mr. President, I yield that time to the Senator from Kentucky. We had a colloquy earlier that maybe we can find some time before 5 for Senator Dorgan to speak. I yield the floor.
If I might, as a manager, we are on strict time limits. At 5 o'clock, Senator Kennedy gets 25 minutes and then 5 minutes goes to Senator Reed. At 5:30, it goes back to the other side. If we take time here and there, it spills over, and someone is going to lose time.
Mr. President, I ask unanimous consent that the order for the quorum call be rescinded.
Mr. President, we are awaiting the arrival of a Senator on our side to speak on the stem cell issues. Until that happens, I will take a couple of minutes to talk about something my friend from Kansas brought up earlier today about adult stem cell treatments.
I am reading a letter from Scienceexpress, a publication of Science magazine. It is entitled, ``Adult Stem Cell Treatments for Diseases?''
Opponents of research with embryonic stem (ES) cells often
claim that adult stem cells provide treatments for 65 human
illnesses. The apparent origin of those claims is a list
created by David A. prentice, an employee of the Family
Research Council who advises U.S. Senator Sam Brownback (R-
KS) and other opponents of ES cell research.
Prentice has said, ``Adult stem cells have now helped
patients with at least 65 different human diseases. It's real
help for real patients''. On 4 May, Senator Brownback stated,
``I ask unanimous consent to have printed in the Record the
listing of 69 different human illnesses being treated by
adult and cord blood stem cells''.
In fact, adult stem cell treatments fully tested in all
required phases of clinical trials and approved by the U.S.
Food and Drug Administration are available to treat only nine
of the conditions on the Prentice list, not 65.
Again, it exposed most of these as kind of being bogus. One of those listed was testicular cancer. Testicular cancer is not being treated with adult stem cells, at least not successfully. In fact, according to the Sciencexpress article, the study that is supposed to be the basis for that claim is actually a study on how to isolate adult stem cells.
The Senator from Kansas also has a list that included several leukemias and lymphomas. Let's hear what George Dahlman of the Leukemia and Lymphoma Society has to say about that.
On behalf of the Leukemia & Lymphoma Society, I am writing
in response to assertions that adult stem cells have treated
or cured several blood cancers, including several leukemias,
lymphomas and multiple myeloma.
As a representative of more than 700,000 patients and their
caregivers in this country that battle blood cancers on a
daily basis, our organization would like to emphasize as the
Senate debates H.R. 810, the Stem Cell Research and
Enhancement Act, that we exist today because we have not
found cures for these devastating diseases. Furthermore, the
claim that treatment of blood cancers with cord blood, blood
or marrow stem cells--known as hematopoietic stem cells--
demonstrates the potential of `adult stem cell' research or
is a substitute for embryonic stem cell research is
misleading and disingenuous.
Mr. Dahlman concludes:
The Leukemia & Lymphoma Society asks that you and your
colleagues pass H.R. 810, and not accept any substitutes.
All in all, according to the science journal, only nine diseases of the 65 examined have proved to even respond to treatment with adult stem cells.
The authors of the analysis conclude that claims about stem cells being in general use for 65 diseases are false. Such claims ``mislead lay people and cruelly deceive patients.''
Again, we are going to hear a lot of talk about all we can do other than embryonic stem cell research. This should not be a debate about whether we do adult stem cells, cord blood, or all these other things. They are all worthy of research.
Those that are for adult stem cell research, cord blood, bone marrow research, that type of thing, all say they want to do that to the exclusion of embryonic stem cells. Those who are in support of H.R. 810 say let's do them all and do them all in an ethically acceptable manner.
Again, we have strong ethical guidelines. One, we do not create any embryos with this bill. You can only use the embryos that are already existing in IVF clinics that are left over that will be discarded. Second, we must have written informed consent of the donors. Third, no one can get paid; no money can change hands. You cannot entice someone to donate these embryos with money. We have strong ethical guidelines.
Lastly, I have heard comments today time and time again about how this bill, H.R. 810, involves the destruction of embryos. I challenge anyone to show me where in H.R. 810 it provides for the destruction of any embryos. Under the Dickey-Wicker amendment that is now existing, no Federal funds can be used to destroy embryos. All H.R. 8l0 says is that once stem cells are derived through private means or whatever, then Federal funds can be used to go to universities or to other researchers to study these embryonic stem cells.
There is nothing in this bill, and I challenge anyone to show me in H.R. 810 where it provides for the destruction of any embryos; it does not. To say otherwise is being disingenuous. The Dickey-Wicker amendment still applies. No Federal money can be used for the destruction of embryos, plain and simple.
I see my colleague from Illinois is here. I yield the floor.
Mr. President, I see the distinguished Senator from Washington is here to make her statement on this bill, and I would yield the floor to Senator Murray for her comments.
Mr. President, I thank the Senator from Washington for her very eloquent statement, and I thank all of the Senators who have come over here today to speak on this important issue.
We have about 20 minutes left in this half hour. I don't have any other Senators right now, but if there are other Senators on our side who wish to take a few minutes to speak on this bill, I would be glad to yield to them.
However, I would like to take this time to sum up, if I can, what we have heard today. We have come to the end of our first day of debate on stem cell research, and I think it has been a very enlightening debate and a very good exposition of the different sides of this issue. I hope the American people who have tuned in to watch this have learned a great deal about why we need to pass H.R. 810, the Stem Cell Research Enhancement Act. As we know, that bill passed the House by a bipartisan majority over a year ago, and I think it has a strong bipartisan majority here in the Senate. Certainly the bill itself is sponsored bipartisanly. If we can pass it tomorrow--and I am confident we can and we will--H.R. 810 can go straight to the President's desk.
I would like to reiterate a few things we have heard today.
First, H.R. 810 has enormous popular support. I have here a letter that was just transmitted to me, and it is a list of different advocacy groups, health organizations, research universities, scientific societies, religious groups, and other interested institutions and associations representing millions of patients, scientists, health care providers, and advocates, writing in strong support for H.R. 810. They point out in this letter that this is the bill which holds promise for expanding medical breakthroughs. The other two bills, the Alternative Pluripotent Stem Cell Therapies Enhancement Act, S. 2754, and the Fetus Farming Prohibition Act, S. 3504, are not substitutes for a ``yes'' vote on H.R. 810.
This letter is signed by 590 advocacy groups. I have been on this Senate floor now 21 years. We all get letters and things that come in expressing support, but I daresay I have never seen anything as overwhelming as this: 590 different groups. Earlier this year, I submitted a list of 205 different groups.
Mr. President, I ask unanimous consent that at the conclusion of my comments on this portion, this list of 590 groups be printed in the Record.
I thank the Presiding Officer.
Again, those are advocacy groups and scientific associations--590.
How about the American people? Three out of four Americans agree: support stem cell research. The question asked in a national poll: Do you support embryonic stem cell research? Seventy-two percent of Americans said yes. Seventy-two percent. That is pretty overwhelming.
I heard the distinguished Senator from Ohio here just a few moments ago say that one of the reasons he was opposed to the bill was because we wanted to do things that would not divide Americans. He thought this would divide Americans. Divide Americans? Seventy-two percent are in favor of it. Over 590 different advocacy groups expressing support, and 205 other disease-related groups all in support. This doesn't divide America at all. Of course, there is always going to be somebody opposed to something around here. But I haven't seen anything that received this much overwhelming support in a long time. As a matter of fact, passing embryonic stem cell research, H.R. 810, will pull Americans together in the fight against disease. And it is bipartisan. As I said, the bill passed the House bipartisanly. The sponsors of the bill itself were three Republicans and three Democrats.
It was stated earlier today a couple of times about a letter that former First Lady Nancy Reagan had written. I thought I would have it blown up and put on a chart for people around the country to take a look at, just to show you how this has nothing to do with partisanship. It shows it is from the office of Nancy Reagan dated May 1, 2006, a letter to Orrin Hatch, Senator Orrin Hatch of Utah, who was one of the cosponsors of this bill. It says:
Dear Orrin:
Thank you for your continued commitment to helping the
millions of Americans who suffer from devastating and
disabling diseases. Your support has given so much hope to so
many.
It has been nearly a year since the United States House of
Representatives first approved the stem cell legislation that
would open the research so we could fully unleash its
promise. For those who are waiting every day for scientific
progress to help their loved ones, the wait for U.S. Senate
action has been very difficult and hard to comprehend.
I understand that the U.S. Senate is now considering voting
on H.R. 810, the Stem Cell Research Enhancement Act, sometime
this month. Orrin, I know I can count on friends like you to
help make sure this happens. There is just no more time to
wait.
Sincerely, Nancy.
When you have seen a loved one suffer from Alzheimer's--I am sure as Mrs. Reagan watched the former President suffer from Alzheimer's--it motivates you to say: Whatever we can do to advance the research, to hopefully get a cure someday, that is what we should do.
For those of us who have friends who have Parkinson's disease, those of us who have seen friends and loved ones die of Lou Gehrig's disease, for those of us who have members of our family or close friends who have had spinal cord injuries, this motivates us to do everything humanly possible to expand this field of research.
My friend Christopher Reeve said, one time when we had watched a film of a rat, a white mouse or white rat, that had its spinal cord damaged so it couldn't walk and then it received embryonic stem cells and then it walked again, Christopher Reeve, former Superman said, ``Oh, to be a rat.''
It holds so much promise, embryonic stem cell research, to ease the suffering and the pain of so many people.
I hear today talk about we have to do adult stem cells; maybe there is not enough money.
Again, I refer to my friend from Ohio, who was here earlier who said funding for medical research is probably going down because of the war and because of Katrina and because of homeland security.
I said: Wait a minute, earlier this year this Senate voted 73 to 27, to put $7 billion back in the budget so we wouldn't cut medical research--73 votes in the Senate. I don't know, 73 votes is pretty overwhelming. It was $7 billion we were supposed to put back in to help medical research. I don't know to what the Senator was referring.
I have heard talk today about adult stem cells and all these other things and how we had adult stem cells do this and adult stem cells do that. Why haven't embryonic stem cells led to treatment as much as adult stem cells have? Scientists have been doing research on adult stem cells for over 30 years, and we still, after 30 years, have not extracted one stem cell line from adult cells--not one.
Now embryonic stem cells were only derived in 1998, 8 years ago, and they have only been getting Federal funding in a limited manner since 2002, under the guidelines the President set down in 2001, which limited the number of stem cell lines to then 78, which we found out later was only 21 stem cell lines.
Again, there are no arbitrary restrictions on research on adult stem cells. Scientists and private companies don't have to be skittish about doing the research. They don't have to worry that all of a sudden the Federal Government is going to ban it or limit it, so they can plan ahead and do long-term research.
Let's compare that situation with human embryonic stem cells. As I said, we didn't derive them until 1998 and the first Federal grant wasn't awarded until 2002. Even now, only a tiny fraction of the total Federal budget for human stem cell research is used for human embryonic stem cells. The vast majority still goes for adult stem cells.
Here it is. I pointed this out earlier today. Human embryonic stem cells in fiscal 2006 from NIH, $38.3 million. Adult stem cells, $200 million. Again, only a tiny fraction going for human embryonic stem cells. Five times as much is going for adult stem cell research. So it is no wonder, after 30 years and all this research and all this money, that more diseases are being treated today with adult stem cells.
Scientists have only been studying embryonic stem cells for 5 years, with
one arm tied behind their back. That one arm being tied their back by the President's proclamation of August 9, 2001, that only stem cell lines derived before 9 p.m. that evening could receive Federal funding. Anything derived after 9 p.m. could not receive Federal funding.
I have wondered ever since, why was it morally acceptable to use stem cell lines derived prior to 9 p.m. on August 9 of 2001 but morally unacceptable for funding of stem cell lines derived after 9 p.m. Can someone please tell me the ethics of that. Can someone please tell me why 9 p.m. on August 9 of 2001 is some kind of a moral dividing line? It is totally arbitrary. The President could have said stem cell lines derived at 10 p.m. or he could have said stem cell lines derived before Christmas of this year. It is the same thing. No one has taken this floor to define why August 9, at 9 p.m, is some kind of a moral dividing line.
The fact is, it doesn't really matter what I think about the potential of embryonic stem cell research. It doesn't matter a heck of a lot what other Senators may think about the potential of embryonic stem cell research. What matters is what does the great body of scientists think about the potential.
The overwhelming majority of reputable biomedical scientists also believes we should pursue embryonic stem cell research; not to the exclusion of others but that we should pursue it.
I have a letter from Dr. J. Michael Bishop who won the Nobel Prize in medicine in 1989. Here is what he says:
The vast majority of the biomedical community believes that
human embryonic stem cells are likely to be the source of key
discoveries relating to many debilitating diseases. In fact,
some of the strongest advocates for human embryonic stem cell
research are those scientists that have devoted their careers
to the study of adult stem cells.
I have a letter from Dr. Alfred G. Gilman, who won the Nobel Prize in medicine in 1994.
It has become obvious, however, that the number of stem
cell lines actually available under current policy is too
small and is controlled by a limited monopoly, which has made
it significantly more difficult and expensive for research to
be conducted. These limits have hindered the important search
for new understanding and treatment of devastating diseases.
I have a letter from the Director of the NIH, Dr. Elias Zerhouni.
Embryonic stem cell research holds great promise for
treating, curing, and improving our understanding of disease.
The breakthroughs are coming. But they take time. They take a lot of scientists researching. This is not something you can put two people on. They need a lot of different lines. Embryonic stem cell research should be ongoing at universities all across America, at our great research institutions, and it ought to be done under the guidance and direction and ethical guidelines of NIH and the ethical guidelines that we have in this bill.
The clampdown on embryonic stem cell research before it even has a chance to start shows a total lack of understanding about how science works, how research works. I have often said that basic research is similar to having 10 doors and they are closed. There is a high probability that behind one of the doors is the answer to your question. If you open one door, you know what the odds are of finding the right answer. If you open two doors, the odds are a little bit better. If you open five doors, the odds are 50-50.
That is what basic research is about. It has been said here a lot of the earlier research on fetal tissue came to nothing. A lot of basic research comes to nothing--in terms of an actual application. But almost all basic research adds to our body of knowledge. Maybe, from one of those basic research grants that was put on the shelf, some other scientist coming along later on might pick something from that, put two or three together and find something.
I am reminded of John Embers, a scientist--I believe he was at Harvard. I will check my facts on that, but I believe he was a doctor at Harvard many years ago. I am talking about a long time ago. I am talking about in the 1940s. He had done some interesting research, basic research on kidney cells of monkeys because they had unique properties. It was a funny research. It was on certain Rhesus monkeys and the oddity of certain kidney cells.
Dr. John Enders didn't get anything for it. He did the research, put it on the shelf, and nothing ever came of it, until a few years later another scientist, examining in another area, remembered Dr. Enders' work, went back and got it, coupled it with his, and came up with something called the Salk polio vaccine. It wasn't until over 25 years later that Dr. John Enders finally received the Nobel Prize for his research.
But I suppose someone 5 years after Dr. Enders had done his research would have said: Why did we spend money on that foolish kind of research? It didn't lead to anything. It kept some scientists employed, but it didn't lead to anything. But Dr. Salk came along, coupled that research with what he was doing and came up with the Salk polio vaccine.
That is a true story.
Again, we have to understand a lot of this is basic research. A lot of it will lead to nothing. But as more and more scientists get involved in examining embryonic stem cells and how they grow, how they multiply, how they differentiate, how they become nerve tissue, how they become brain tissue, how they become skin tissue, how they become blood tissues--as they begin to investigate that, I am sure there will be a lot of blind alleys. But I submit that everything that is done builds the body of scientific evidence that we need, the science that will eventually lead to a cure of a disease. That is the promise of embryonic stem cell research. To stop it now or to limit it doesn't make sense.
People talk about the ethics and morality. I have heard talk about we have to protect innocent life. This is an embryo; an embryo with 100 cells, 200 cells. You can take whatever view you want of that embryo. The point is that the bill we are talking about does not destroy one embryo. It only says that we can get funding for the research on those. These are embryos that are going to be discarded anyway, in in vitro fertilization clinics. They are being discarded every day.
Why don't people come out and say: Stop in vitro fertilization. Make it a crime. You don't hear anybody saying that because 50,000 babies were born last year to people who wanted to have a baby and couldn't have one and used in vitro fertilization. Once they have their children, they call up the in vitro clinic and say: I don't want the remaining embryos, just discard them. I ask you, what is the moral thing to do, just discard them or, with the written consent of the donors, use those embryonic stem cells to save lives and ease suffering and cure disease? That, to me, is the moral and the ethical choice.
I see my time is up and I yield the floor.
Exhibit 1
U.S. Senate,
Washington, DC, July 14, 2006.
Dear Senator: We, the undersigned patient advocacy groups,
health organizations, research universities, scientific
societies, religious groups and other interested institutions
and associations, representing millions of patients,
scientists, health care providers and advocates, write you
with our strong and unified support for H.R. 810, the Stem
Cell Research Enhancement Act. We urge your vote in favor of
H.R. 810 when the Senate considers the measure next week.
Of the bills being considered simultaneously, only H.R. 810
will move stem cell research forward in our country. This is
the bill which holds promise for expanding medical
breakthroughs. The other two bills--the Alternative
Pluripotent Stem Cell Therapies Enhancement Act (S. 2754) and
the Fetus Farming Prohibition Act (S. 3504)--are NOT
substitutes for a YES vote on H.R. 810.
H.R. 810 is the pro-patient and pro-research bill. A vote
in support of H.R. 810 will be considered a vote in support
of more than 100 million patients in the U.S. and substantial
progress for research. Please work to pass H.R. 810
immediately.
Sincerely,
A O North America; AAALAC International; AARP; Abbott
Laboratories; Acadia Pharmaceuticals; Accelerated Cure
Project for Multiple Sclerosis; Adams County Economic
Development, Inc.; AdvaMed (Advanced Medical Technology
Association); Affymetrix, Inc.; Albert Einstein College
of Medicine of Yeshiva University; Alliance for Aging
Research; Alliance for Lupus Research; Alliance for
Stem Cell Research; Alnylam US, Inc.; Alpha-1
Foundation; ALS Association; Ambulatory Pediatric
Association; AMDeC-Academic Medicine Development Co.;
America on the Move Foundation; American Academy of
Neurology.
American Academy of Nursing; American Academy of
Pediatric Dentistry; American Academy of Pediatrics;
American Association for Cancer Research;
American Association for Dental Research; American
Association for Geriatric Psychiatry; American
Association for the Advancement of Science; American
Association of Anatomists; American Association of
Colleges of Nursing; American Association of Colleges
of Osteopathic Medicine; American Association of
Colleges of Pharmacy; American Association of
Neurological Surgeons/Congress of Neurological
Surgeons; American Association of Public Health
Dentistry; American Autoimmune Related Diseases
Association; American Brain Coalition; American Chronic
Pain Association; American College of Cardiology;
American College of Medical Genetics; American College
of Neuropsychopharmacology; American College of
Obstetricians and Gynecologists.
American College of Surgeons; American Council on
Education; American Council on Science and Health;
American Dental Association; American Dental Education
Association; American Diabetes Association; American
Federation for Aging Research; American
Gastroenterological Association; American Geriatrics
Society; American Institute for Medical and Biological
Engineering; American Lung Association; American
Medical Association; American Medical Informatics
Association; American Medical Women's Association;
American Pain Foundation; American Parkinson's Disease
Association; American Parkinson's Disease Association
(Arizona Chapter); American Pediatric Society; American
Physiological Society; American Psychiatric
Association.
American Psychological Association; American Public
Health Association; American Society for Biochemistry
and Molecular Biology; American Society for Bone and
Mineral Research; American Society for Cell Biology;
American Society for Clinical Pharmacology and
Therapeutics; American Society for Microbiology; American
Society for Neural Transplantation and Repair; American
Society for Nutrition; American Society for Pharmacology
and Experimental Therapeutics; American Society for
Reproductive Medicine; American Society for Virology;
American Society of Clinical Oncology; American Society of
Critical Care Anesthesiologists; American Society of
Hematology; American Society of Human Genetics; American
Society of Nephrology; American Society of Tropical
Medicine and Hygiene; American Surgical Association;
American Surgical Association Foundation.
American Thoracic Society; American Thyroid Association;
American Transplant Foundation; Americans for Medical
Progress; amFAR, The Foundation for AIDS Research;
Arizona State University College of Nursing; Arthritis
Foundation; Arthritis Foundation, Rocky Mountain
Chapter; Association for Clinical Research Training;
Association for Medical School Pharmacology Chairs;
Association for Prevention Teaching and Research;
Association for the Accreditation of Human Research
Protection Programs, Inc.; Association of Academic
Chairs of Emergency Medicine; Association of Academic
Departments of Otolaryngology; Association of Academic
Health Centers; Association of Academic Physiatrists;
Association of American Medical Colleges; Association
of American Physicians; Association of American
Universities; Association of American Veterinary
Medical Colleges.
Association of Anatomy, Cell Biology and Neurobiology
Chairs; Association of Anesthesiology Program
Directors; Association of Black Cardiologists;
Association of Chairs of Departments of Physiology;
Association of Independent Research Institutes;
Association of Medical School Microbiology and
Immunology Chairs; Association of Medical School
Pediatric Department Chairs; Association of Medical
School Pharmacology Chairs; Association of Professors
of Dermatology; Association of Professors of Human and
Medical Genetics; Association of Professors of
Medicine; Association of Public Health Laboratories;
Association of Reproductive Health Professionals;
Association of Schools and Colleges of Optometry;
Association of Specialty Professors; Association of
University Anesthesiologists; Assurant Health; Asthma
and Allergy Foundation of America; Athena Diagnostics;
Aurora Economic Development Council.
Axion Research Foundation; B'nai B'rith International;
Baylor College of Medicine; Baylor College of Medicine
Graduate School of Biomedical Sciences; Biotechnology
Industry Organization; BloodCenter of Wisconsin, Inc.;
Blue Cross and Blue Shield Foundation on Health Care;
Boston Biomedical Research Institute; Boston University
School of Dental Medicine; Boston University School of
Public Health; Brigham and Women's Hospital; Bristol-
Myers Squibb Company; Broadened Horizons, LLC; Brown
Medical School; Buck Institute for Age Research; Bums &
Allen Research Institute; Burrill & Company; Burroughs
Wellcome Fund; C3: Colorectal Cancer Coalition;
California Biomedical Research Association.
California Institute of Technology; California Institute
for Regenerative Medicine; California Wellness
Foundation; Californians for Cures; Campaign for
Medical Research; Cancer Research and Prevention
Foundation; Canon U.S. Life Sciences, Inc.; Case
Western Reserve University School of Dentistry; Case
Western Reserve University School of Medicine; Cedars-
Sinai Health System; Center for the Advancement of
Health; Central Conference of American Rabbis; CFIDS
Association of America; Charles R. Drew University of
Medicine and Science; Charles River Laboratories; Child
& Adolescent Bipolar Foundation; Children's Memorial
Research Center; Children's Neurobiological Solutions
Foundation; Children's Research Institute (Columbus);
Children's Research Institute (Washington).
Children's Tumor Foundation; Childrens Hospital Boston;
Christopher Reeve Foundation; City and County of
Denver; City of Hope National Medical Center; Cold
Spring Harbor Laboratory; Coleman Institute for
Cognitive Disabilities, University of Colorado System;
Colfax Marathon Partnership, Inc.; Colorado Bioscience
Association; Colorado Office of Economic Development
and International Trade; Colorado State University;
Columbia University; Columbia University College of
Dental Medicine; Columbia University Medical Center;
Community Health Partnership; Conference of Boston
Teaching Hospitals; Connecticut United for Research
Excellence, Inc.; Conquer Fragile X Foundation; Cornell
University; Council for the Advancement of Nursing
Science (CANS).
Creighton University School of Medicine; CURE (Citizens
United for Research in Epilepsy); Cure Alzheimer's
Fund; Cure Paralysis Now; CuresNow; Damon Runyon Cancer
Research Foundation; Dana-Farber Cancer Institute;
Dartmouth Medical School; David Geffen School of
Medicine at UCLA; DENTSPLY International; Digene
Corporation; Discovery Partners International; Doheny
Eye Institute; Drexel University College of Medicine;
Drexel University School of Public Health; Duke
University Medical Center; Dystonia Medical Research
Foundation; East Tennessee State University James H.
Quillen College of Medicine; Eli Lilly and Company;
Elizabeth Glaser Pediatric AIDS Foundation.
Emory University; Emory University Nell Hodgson Woodruff
School of Nursing; Emory University Rollins School of
Public Health; Emory University School of Medicine;
FasterCures; FD Hope Foundation; Federation of American
Scientists; Federation of American Societies for
Experimental Biology (FASEB); Federation of State
Medical Boards of the United States, Inc.; Fertile
Hope; Fitzsimons Redevelopment Authority; Florida
Atlantic University Division of Research; Ford Finance,
Inc.; Fox Chase Cancer Center; Fred Hutchinson Cancer
Research Center; Friends of Cancer Research, Friends of
the National Institute for Dental and Craniofacial
Research, Friends of the National Institute of Nursing
Research; Friends of the National Library of Medicine;
Genetic Alliance.
Genetics Policy Institute; George Mason University;
Georgetown University Medical Center; Guillain Barre
Syndrome Foundation International; Gynecologic Cancer
Foundation; Hadassah; Harvard University; Harvard
University School of Dental Medicine; Harvard
University School of Public Health; Hauptman-Woodward
Medical Research Institute, Inc.; Hereditary Disease
Foundation, HHT Foundation International, Inc.; Home
Safety Council; Howard University College of Dentistry;
Howard University College of Medicine; Huntington's
Disease Society of America; IBM Life Sciences Division;
Illinois State University Mennonite College of Nursing;
ImmunoGen, Inc.; Indiana University School of
Dentistry.
Indiana University School of Medicine; Indiana University
School of Nursing; Infectious Diseases Society of
America; Institute for African American Health, Inc.;
Intercultural Cancer Council Caucus; International
Foundation for Anticancer Drug Discovery (IFADD);
International Longevity Center--USA; International
Society for Stem Cell Research; Invitrogen Corporation;
Iraq Veterans for Cures; Iris Alliance Fund; Iron
Disorders Institute; Jacobs Institute of Women's
Health; Jeffrey Modell Foundation; Johns Hopkins; Johnson
& Johnson; Joint Commission on Accreditation of Healthcare
Organizations (JCAHO); Joint Steering Committee for Public
Policy; Juvenile Diabetes Research Foundation; Keck School
of Medicine of the University of Southern California.
Kennedy Krieger Institute; Keystone Symposia on Molecular
and Cellular
Biology; KID Foundation; Kidney Cancer Association; La
Jolla Institute for Allergy and Immunology; Lance
Armstrong Foundation; Lawson Wilkins Pediatric
Endocrine Society; Leukemia and Lymphoma Society;
Lombardi Comprehensive Cancer Center, Georgetown
University; Los Angeles Biomedical Research Institute
at Harbor-UCLA Medical Center; Louisiana State
University Health Sciences Center; Louisiana State
University Health Sciences Center School of Dentistry;
Lovelace Respiratory Research Institute; Loyola
University of Chicago Stritch School of Medicine; Lung
Cancer Alliance; Lupus Foundation of America, Inc.;
Lupus Foundation of Colorado, Inc.; Lupus Research
Institute; Lymphatic Research Foundation; Mailman
School of Public Health of Columbia University.
Malecare Prostate Cancer Support; March of Dimes Birth
Defects Foundation; Marine Biological Laboratory;
Marshalltown [IA] Cancer Resource Center; Masonic
Medical Research Laboratory; Massachusetts
Biotechnology Council; Massachusetts General Hospital;
Massachusetts Institute of Technology; MaxCyte, Inc.;
McLaughlin Research Institute; Medical College of
Georgia; Medical University of South Carolina; Medical
University of South Carolina College of Nursing;
MedStar Research Institute (MRI); Meharry Medical
College School of Dentistry; Memorial Sloan-Kettering
Cancer Center; Memory Pharmaceuticals; Mercer
University; Metro Denver Economic Development
Corporation; Miami Children's Hospital.
Midwest Nursing Research Society; Morehouse School of
Medicine; Mount Sinai Medical Center; Mount Sinai
School of Medicine; National Alliance for Eye and
Vision Research; National Alliance for Hispanic Health;
National Alliance for Research on Schizophrenia and
Depression; National Alliance on Mental Illness;
National Alopecia Areata Foundation; National Asian
Women's Health Organization; National Association for
Biomedical Research; National Association of Hepatitis
Task Forces; National Caucus of Basic Biomedical
Science Chairs; National Coalition for Cancer Research;
National Coalition for Cancer Survivorship; National
Coalition for Women with Heart Disease; National
Committee for Quality Health Care; National Council of
Jewish Women; National Council on Spinal Cord Injury;
National Down Syndrome Society.
National Electrical Manufacturers Association; National
Foundation for Ectodermal Dysplasias; National Health
Council; National Hemophilia Foundation; National
Hispanic Health Foundation; National Jewish Medical and
Research Center; National Marfan Foundation; National
Medical Association; National Multiple Sclerosis
Society; National Osteoporosis Foundation; National
Partnership for Women and Families; National
Pharmaceutical Council; National Prostate Cancer
Coalition; National Quality Forum; National Spinal Cord
Injury Association; National Venture Capital
Association; Nebraskans for Research; Nemours; New
Jersey Association for Biomedical Research; New Jersey
Dental School.
New York Blood Center; New York College of Osteopathic
Medicine; New York State Association of County Health
Officials; New York Stem Cell Foundation; New York
University College of Dentistry; New York University
School of Medicine; New York-Presbyterian Hospital;
North American Brain Tumor Coalition; North Carolina
Association for Biomedical Research; Northwest Association
for Biomedical Research; Northwestern University;
Northwestern University, The Feinberg School of Medicine;
Nova Southeastern University College of Dental Medicine;
Novartis Pharmaceuticals; Oklahoma Medical Research
Foundation; Oral Health America; Oregon Health & Science
University; Oregon Health & Science University School of
Nursing; Oregon Research Institute; Oxford Bioscience
Partners.
Pacific Health Research Institute; Paralyzed Veterans of
America; Parent Project Muscular Dystrophy; Parkinson's
Action Network; Parkinson's Disease Foundation;
Partnership for Prevention; Pennsylvania Society for
Biomedical Research; Pharmaceutical Research and
Manufacturers of America; Pittsburgh Development
Center; Princeton University; Project A.L.S.; Prostate
Cancer Foundation; Pseudoxanthoma Elasticum
International; Quest for the Cure; RAND Health;
Research! America; Resolve: The National Infertility
Association; RetireSafe; Rett Syndrome Research
Foundation; Rice University.
Robert Packard Center for ALS Research at Johns Hopkins;
Rosalind Franklin University of Medicine and Science;
Rush University Medical Center; Rutgers University;
Salk Institute for Biological Studies; sanofi-aventis;
Scleroderma Research Foundation; Secular Coalition for
America; Sjogren's Syndrome Foundation, Inc.; Society
for Advancement of Violence and Injury Research
(SAVIR); Society for Assisted Reproductive Technology;
Society for Education in Anesthesia; Society for Male
Reproduction and Urology; Society for Neuroscience;
Society for Pediatric Research; Society for
Reproductive Endocrinology and Infertility; Society for
Women's Health Research; Society of Academic
Anesthesiology Chairs; Society of General Internal
Medicine; Society of Gynecologic Oncologists.
Society of Reproductive Surgeons; Society of University
Otolaryngologists; South Alabama Medical Science
Foundation; South Dakota State University; Southern
Illinois University School of Medicine; Spina Bifida
Association of America; Stanford University; State
University of New York at Buffalo School of Dental
Medicine; State University of New York Downstate
Medical Center College of Medicine at Brooklyn; State
University of New York Upstate Medical University; Stem
Cell Action Network; Stem Cell Research Foundation;
Steven and Michele Kirsch Foundation; Stony Brook
University, State University of New York; Strategic
Health Policy International, Inc.; Student Society for
Stem Cell Research; Suicide Prevention Action Network-
USA (SPAN); Take Charge! Cure Parkinson's, Inc.;
Targacept, Inc.;
Temple University School of Dentistry; Texans for
Advancement of Medical Research; Texas A&M University
Health Science Center; Texas Medical Center; Texas Tech
University Health Sciences Center; The Arc of the
United States; The Association for Research in Vision
and Ophthalmology; The Biophysical Society; The Brody
School of Medicine at East Carolina University; The
Burnham Institute; The CJD Foundation; The Critical
Path Institute (C-Path); The Endocrine Society; The
FAIR Foundation; The Food Allergy and Anaphylaxis
Network; The Food Allergy Project, Inc.; The Forsyth
Institute; The Foundation Fighting Blindness; The
George Washington University Medical Center. The
Georgetown University Center for the Study of Sex
Difference in Health, Aging and Disease.
The Gerontological Society of America; The J. David
Gladstone Institutes; The Jackson Laboratory; The Johns
Hopkins University Bloomberg School of Public Health;
The Johns Hopkins University School of Nursing; The
Medical College of Wisconsin; The Medical Foundation,
Inc., The Michael J. Fox Foundation for Parkinson's
Research; The Ohio State University College of
Dentistry; The Ohio State University College of
Medicine and Public Health; The Ohio State University
School of Public Health; The Parkinson Alliance and
Unity Walk; The Research Foundation for Mental Hygiene,
Inc.; The Rockefeller University; The Schepens Eye
Research Institute; The Scientist; The Scripps Research
Institute; The Smith-Kettlewell Eye Research Institute;
The Society for Investigative Dermatology; The Spiral
Foundation.
The University of Chicago Pritzker School of Medicine;
The University of Iowa Carver College of Medicine; The
University of Iowa College of Dentistry; The University
of Iowa College of Public Health; The University of
Mississippi Medical Center; The University of
Mississippi Medical Center School of Dentistry; The
University of Oklahoma College of Dentistry; The
University of Oklahoma Health Sciences Center; The
University of Tennessee Health Science Center; The
University of Tennessee HSC College of Nursing; The
University of Texas Health Science Center at Houston;
The University of Texas Health Science Center at San
Antonio; The University of Texas M.D. Anderson Cancer
Center; The University of Texas Medical Branch at
Galveston School of Medicine; The University of Texas
Southwestern Medical Center; The University of Toledo
Academic Health Science Center; Tourette Syndrome
Association; Travis Roy Foundation; Tufts University
School of Dental Medicine; Tulane University.
Tulane University Health Sciences Center; Union for
Reformed Judaism; Union of Concerned Scientists;
Unitarian Universalist Association of Congregations;
United Spinal Association; University of Alabama at
Birmingham School of Medicine; University of Alabama at
Birmingham School of Nursing; University of Alabama at
Birmingham School of Public Health; University of
Arizona College of Medicine; University of Arkansas for
Medical Sciences; University of Buffalo; University of
California System; University of California, Berkeley;
University of California, Berkeley School of Public
Health; University of California, Davis; University of
California, Irvine; University of California, Los
Angeles; University of California, Los Angeles School
of Dentistry; University of California, Los Angeles
School of Medicine; University of California, San
Diego.
University of California, San Francisco; University of
California, San Francisco School of Dentistry;
University of California, San Francisco School of
Nursing; University of California, Santa Cruz;
University of Chicago; University of Cincinnati Medical
Center; University of Colorado at Denver and Health
Sciences Center; University of Colorado at Denver and
HSC School of Dentistry; University of Colorado at
Denver and HSC School of Nursing; University of
Connecticut School of Medicine; University of Florida;
University of Florida College of Dentistry; University
of Georgia; University of Illinois; University of
Illinois at Chicago; University of Illinois at Chicago
College of Dentistry; University of Illinois at Chicago
College of Nursing; University of Iowa; University of
Kansas; University of Kansas Medical Center.
University of Kansas Medical Center School of Nursing;
University of Kentucky; University of Kentucky College
of Dentistry; University of Louisville; University of
Louisville School of Dentistry; University of Maryland
at Baltimore; University of Maryland at Baltimore
College of Dental Surgery; University of Maryland at
Baltimore School of Nursing; University of Miami;
University of Michigan; University of Michigan College
of Pharmacy; University of Michigan Medical
School; University of Michigan School of Dentistry;
University of Michigan School of Nursing; University of
Michigan School of Public Health; University of Minnesota;
University of Minnesota School of Public Health;
University of Missouri at Kansas City School of Dentistry;
University of Montana School of Pharmacy and Allied Health
Sciences; University of Nebraska Medical Center.
University of Nebraska Medical Center College of
Dentistry; University of Nevada, Las Vegas School of
Dental Medicine; University of Nevada, Reno School of
Medicine; University of North Carolina at Chapel Hill;
University of North Carolina at Chapel Hill School of
Dentistry; University of North Carolina at Chapel Hill
School of Public Health; University of North Dakota;
University of North Texas Health Science Center;
University of Oregon; University of Pennsylvania School
of Dental Medicine; University of Pennsylvania School
of Medicine; University of Pennsylvania School of
Nursing; University of Pittsburgh Graduate School of
Public Health; University of Pittsburgh School of
Dental Medicine; University of Pittsburgh School of
Medicine; University of Rochester Medical Center;
University of Rochester School of Medicine and
Dentistry; University of Rochester School of Nursing;
University of South Carolina Office of Research and
Health Sciences; University of South Dakota School of
Medicine and Health Sciences.
University of South Florida; University of South Florida
College of Nursing; University of Southern California;
University of Southern California School of Dentistry;
University of Utah HSC School of Medicine; University
of Vermont College of Medicine; University of
Washington; University of Washington School of
Dentistry; University of Washington School of Nursing;
University of Washington School of Public Health and
Community Medicine; University of Wisconsin-Madison;
Van Andel Research Institute; Vanderbilt University and
Medical Center; Vanderbilt University School of
Nursing; Virginia Commonwealth University School of
Dentistry; Virginia Commonwealth University School of
Medicine; Wake Forest University School of Medicine;
Washington University in St. Louis; Washington
University in St. Louis Center for Health Policy;
Washington University in St. Louis School of Medicine.
WE MOVE; Weill Medical College of Cornell University;
Whitehead Institute for Biomedical Research; WiCell
Research Institution; Wisconsin Alumni Research
Foundation; Wisconsin Association for Biomedical
Research and Education; Woodruff Health Sciences Center
at Emory University; Wright State University; School of
Medicine; Yale University; Yale University School of
Medicine; Yale University School of Nursing.
If the Senator would yield, I understand the Senator from Virginia wanted 10 minutes. I said I didn't intend to speak for half an hour; I just wanted to speak for about 5 minutes at 8 o'clock and yield back the remainder of my time and he could speak as long as he wanted to at that time. It is only 15 minutes from now. I thought the Senator from Kansas was probably going to use up most of the time.
I say to the Senator from Virginia, go ahead and take your time. I will speak later. That is fine.
(The remarks of Mr. Warner are printed in today's Record under ``Morning Business.'')
Mr. President, I will not take the entire 25 minutes that are left, but I did want to close out a little bit today before we proceed into tomorrow by just responding to a few of the things that were said today to try to clear up a couple of issues.
The Senator from Kansas, my good friend, was going on and on about stem cells, as he has most of the day, and about how all these treatments and everything are out there. I could respond to every one of them, but I think what we have to keep in mind is that if all of these diseases that the Senator from Kansas talked about have been treated with adult stem cells, how come all of the patient advocacy groups for these diseases support H.R. 810?
One has to wonder, when you listen to the Senator from Kansas outline all these diseases that are being helped by adult stem cells. He brings up the picture of the guy who had Parkinson's. He was helped with adult stem cells. But, again, he has now gone back and he is where he was before.
Well, if adult stem cells are doing so much, why is the Parkinson's group, the Parkinson's Action Network, supporting H.R. 810? Why are all these advocacy groups supporting H.R. 810 if adult stem cells are so great? Are they just a bunch of stupid people out there? Have they been hoodwinked and misguided?
These advocacy groups know. They know what is going on. And they know that S. 2754 is no substitute for H.R. 810. While adult stem cells are fine, as I pointed out earlier, they have been investigating and doing science on adult stem cells for over 30 years.
Now, just another little thing that happened: The Senator from Kansas, I heard him say: Well, they have been investigating animal stem cells for 20 years.
That might lead you to think: Well, we have been looking at stem cells for 20 years. Not so. We never derived human embryonic stem cells until 1998--8 years ago. So I wanted to make the record clear on that.
Now, the Senator also mentioned something about testicular cancer. He made all kinds of claims about adult stem cells helping testicular cancer. Let me read from a letter written by Craig Nichols, MD, a member of the board of the Lance Armstrong Foundation. We all know the Lance Armstrong Foundation is basically focused on testicular cancer because that is what Lance Armstrong had. And he licked it. But let me quote from the letter written on July 14:
Dear Senator Frist:
As a member of the Lance Armstrong Foundation's Board of
Directors, I am writing in response to assertions that adult
stem cells have treated or cured the disease of testicular
cancer. . . . I feel that it is important to set the record
straight on this issue.
Testicular cancer is the most common cancer among men ages
15-35 and approximately 8,000 men will be diagnosed with
testicular cancer in the United States this year. While
testicular cancer is one of the most curable forms of cancer,
our organization would like to emphasize as the Senate
debates H.R. 810 . . . that we have NOT completely eradicated
the disease.
There is not an FDA-approved adult stem cell treatment
generally available to treat testicular cancer.
The Senator from Kansas kind of, in his comments, led us to think that there might be. Here is what Dr. Nichols said:
Rather, adult stem cells enable testicular cancer patients
to withstand a higher dose of chemotherapy during treatment
for the disease.
The adult stem cells enable patients to withstand a higher dose of chemotherapy. Dr. Nichols says:
We support exploring every avenue of research, including
embryonic stem cell research within specified ethical limits,
until a cure is found. . . .
The Lance Armstrong Foundation asks that you and your
colleagues pass H.R. 810, and not accept any substitutes.
I ask unanimous consent that this letter from the Lance Armstrong Foundation be printed in the Record.
Now, we hear claims that leukemia and lymphomas have been cured or treated by adult stem cells. Here is what George Dahlman of the Leukemia and Lymphoma Society has to say about that:
On behalf of the Leukemia and Lymphoma Society, I am
writing in response to assertions that adult stem cells have
treated or cured several blood cancers, including several
leukemias, lymphomas and multiple myeloma.
As a representative of more than 700,000 patients and their
caregivers in this country that battle blood cancers on a
daily basis, our organization would like to emphasize, as the
Senate debates H.R. 810 . . . that we exist today because we
have not found cures for these devastating diseases. . . .
the claim that treatment of blood cancers with cord blood,
blood or marrow stem cells--known as hematopoietic stem
cells--demonstrates a potential of ``adult stem cell''
research or is a substitute of embryonic stem cell research
is misleading and disingenuous.
Again, this says that the claim that treatment of blood cancer with marrow stem cells demonstrates that adult stem cells is a substitute is misleading and disingenuous.
Mr. Dahlman concludes:
The Leukemia and Lymphoma Society asks that you and your
colleagues pass H.R. 810, and not accept any substitutes.
Mr. President, we have heard a lot of talk about these embryos and that we all started as a dot. I have often used this example. I have said: What is an embryo? I have often put a dot on a piece of paper and held it up for audiences to see and said that is what we are talking about. It is that big, the size of a period at the end of a sentence. That is not to diminish the importance of an embryo. But I use it in comparison. An embryo at the blastocyst stage has between 100 and 200 cells. That embryo we are talking about that is in an in vitro fertilization clinic and frozen in liquid nitrogen will never become a human being unless and until it is implanted into a uterus and it takes hold and develops. Sometimes they are implanted and they don't take hold and they are discharged. So an embryo is potential life--potential in that if it is implanted and takes hold, it could become a human being. It is potential life.
Look at this photo of Lauren Stanford. She says:
I am so happy to hear that the Senate is thinking of
passing H.R. 810. I can dream again--dream of that great day
when I write a thank you letter to the Senate, the House, and
everyone who helped me become just another girl; a girl who
dreamed and hoped and one day got just what she wanted; her
health and future.
Lauren Stanford has diabetes. She knows what will happen if she is not cured. At some point in her life, she will probably become blind. At some point in her life, she will probably lose a foot, a leg, one or more of her limbs. At some point in her life, diabetes will take her. Lauren Stanford. I don't know her. I don't know that I ever met Lauren Stanford. This is not potential life; this is real life. This is a human being who is living right now.
That dot on the paper is an embryo. Is it alive? Of course it is alive. Is it a human being? No. It is potential life. Lauren Stanford is real life.
Read the bill. Read H.R. 810. Ethical guidelines. We can only use those embryos that are left over from in vitro
fertilization that are going to be discarded. Read the bill:
Prior to the consideration of embryo donation and through
consultation with the individuals seeking fertility
treatment, it was determined that the embryos would never be
implanted in a woman and would otherwise be discarded.
Written consent.
The individuals seeking fertility treatment donated the
embryos with written informed consent and without receiving
any financial or other inducements to make the donation.
It has to be determined, before any embryo could ever be used for stem cell derivation, that the embryos would never be implanted in a woman and would otherwise be discarded. Every day, fertility clinics discard unwanted embryos. People have IVF--50,000 babies were born last year to couples who wanted to have a baby and could not and needed IVF. But some embryos were left over. Well, couples who have had their children then call up the clinic or the clinic calls them and the clinic says: Do you want to continue to pay for us to keep these embryos frozen?
If you have had your children and you don't want to expand your family, you say: No, I don't want to pay for that anymore. Guess what. The IVF clinic discards it. I have heard they basically throw them in the sink and wash them down the sink. They are only as big as a period at the end of a sentence.
So the real question for us really comes down to that, unless we want to outlaw in vitro fertilization and make it a crime, which I don't hear anybody here wanting to do. As long as we have in vitro fertilization and have leftover embryos, the real question for us is this: If the donors of those embryos, through written informed consent, determine it will never be implanted in a woman and will be discarded, is it better to have them discarded and flushed down the drain or used for the kind of scientific research that will cure Lauren Stanford of her diabetes? Potential life versus real life. Potential life that will be discarded versus real life. Potential life that will be flushed down the drain versus Lauren Stanford, real life. That is the question for us.
We hear all of these arguments around here about we were all an embryo at one time. Of course we were. The question is, What happens to all those embryos? Right now, they are being discarded, and it is perfectly legal to do so. I don't see anyone here with legislation saying it is going to be a crime for them to be discarded, a crime to have in vitro fertilization. Really, that is the choice. Do we discard potential life or do we use it to save real life? This is not potential life, this is real.
My nephew Kelly, who suffered a tragic accident on an aircraft carrier 27 years ago, hasn't walked since. He keeps hope alive that one day he will walk again. He knows about the research that has been done on rats and mice where spinal cords have been reconnected using embryonic stem cells. He knows that. I have never heard him say it, but I suppose he would probably echo what Christopher Reeve once said: Oh, to be a rat.
He knows that. That is real life. Kelly is a real person. He is alive. He is not potential life. That is our decision when we face the vote tomorrow on H.R. 810.
So all these other arguments about adult stem cells and this kind of stuff, fine, I have nothing against adult stem cell research. I am in favor of it. We ought to keep it going. But to choke off--not what I say but what the leading scientists say, the leading Nobel Prize winners say, what all of these disease groups who have medical people sitting on their boards, what they all say is the most promising avenue of research for curing Alzheimer's, juvenile diabetes, spinal cord injuries, Parkinson's, and ALS, the most promising is not adult stem cells. It is embryonic stem cells. That is what they say, not me.
To cut that off and to say, no, we won't do it is telling Lauren Stanford that potential life, that an embryo the size of a pencil dot, yes, is life; it is human potential that is as important as she is; that they have equal weight on the scales. I am sorry, Mr. President, I don't think so, not when it is going to be discarded, legally thrown down the drain. And as long as we have strict ethical guidelines in the bill--strict ethical guidelines, more than exists right now, stronger ethical guidelines than are in the law right now.
To me, there is really only one answer. We should be in favor of this real life of curing diseases, seeking treatments and cures in an ethical manner, which is what this bill does. So I hope that tomorrow we have an overwhelming vote in favor of H.R. 810.
I understand today the administration came out with a Statement of Administration Policy, or SAP as it is called around here, saying the President would veto it. I hope the President rethinks this. He is overseas anyway. Let's face it, we are all kind of captives of our staff around here. Staff tells us this and that. OMB says this, OMB says that. I am hopeful this is the work of some staff, that the President hasn't thought about it. He has been overseas focused on the G8; now, I am sure, focused on the Middle East.
I hope when President Bush thinks about it that he remembers Lauren Stanford, that he will remember the letter from Nancy Reagan and he will come down on the side of real life, and he will come down on the side of an ethical approach to embryonic stem cell research.
I still believe in miracles, and I hope a miracle will occur and the President of the United States finds it in his heart to say that what he did on August 9, 2001, was done with a lack of adequate knowledge. He can say: Look, we thought there were 78 lines, and there were not; there were only 21 lines. We didn't know they were all contaminated with mouse feeder cells. They can't be used for human therapies. That he will say in light of all that we know now, and with the strict ethical guidelines we have in this bill, I see fit to sign into law