S. 1553Senate115th Congress (2017-2019)In Committee

Stopping Overdoses of Fentanyl Analogues Act

Introduced July 13, 2017

AI-Generated Summary

Updated April 15, 2026 at 4:56 PM UTC

The Stopping Overdoses of Fentanyl Analogues Act would change the federal drug scheduling system by moving fentanyl analogues into Schedule I, the category for substances with no accepted medical use and a high potential for abuse. It adds a list of specific fentanyl‑related chemicals to Schedule I and creates a broad definition that captures any chemically similar compounds, their salts, isomers, or mixtures. The change would affect anyone who manufactures, distributes, possesses, or uses these substances, including law‑enforcement and public‑health agencies.

Key Provisions

  • Adds a list of fifteen named fentanyl analogues (e.g., acetyl fentanyl, acrylfentanyl, ocfentanil) to Schedule I of the Controlled Substances Act.
  • Defines “fentanyl analogues” broadly to include any compound structurally derived from fentanyl by various substitutions or replacements, covering salts, isomers, and mixtures.
  • Specifies that any material containing any fentanyl analogue—or its salts, isomers, or related forms—is automatically treated as a Schedule I substance unless specifically exempted or placed in another schedule.

Legislative Activity

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1 earlier action
SenateIntro Referral Latest Action

Read twice and referred to the Committee on the Judiciary. (Sponsor introductory remarks on measure: CR S3999-4000)

July 13, 2017

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SenateIntro Referral

Introduced in Senate

July 13, 2017

SenateIntro Referral

Read twice and referred to the Committee on the Judiciary. (Sponsor introductory remarks on measure: CR S3999-4000)

July 13, 2017

Floor Debate

6 members

What members said about S. 1553 on the floor

5 Republicans1 Democrat
Roy Blunt
Sen. Roy BluntR-MO · Jul 13, 2017

Madam President, it has been nearly 7 months since President Trump took office. He was sworn in on the steps of the Capitol on January 20. Our colleagues across the aisle have had, frankly, more than…

Ron Johnson
Sen. Ron JohnsonR-WI · Jul 13, 2017

Mr. President, I rise today to discuss an epidemic that is sweeping our Nation. From big cities to small towns, communities across our country have been ravaged by drug addiction and the multiple…

Ron Johnson
Sen. Ron JohnsonR-WI · Jul 13, 2017

Mr. President, I rise today to discuss an epidemic that is sweeping our Nation. From big cities to small towns, communities across our country have been ravaged by drug addiction and the multiple…

Jeff Flake
Sen. Jeff FlakeR-AZ · Jul 13, 2017

Mr. President, I rise to speak about a critical subject too often overlooked by Congress. It is the Federal debt and our deficit. It is no secret that our national debt will soon surpass $20…

John McCain
Sen. John McCainR-AZ · Jul 13, 2017

Mr. President, I come to the floor today to introduce the Open America's Waters Act of 2017. This bill would repeal the Merchant Marine Act of 1920, better known as the Jones Act, an archaic and…

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Richard J. Durbin
Sen. Richard J. DurbinD-IL · Jul 13, 2017

Mr. President, I ask unanimous consent that the text of the bill be printed in the Record.

Dan Sullivan
Sen. Dan SullivanR-AK · Jul 13, 2017

Mr. President, I ask unanimous consent that the order for the quorum call be rescinded.

Ron Johnson
Sen. Ron JohnsonR-WI · Jul 13, 2017

Madam President, I yield the floor. I suggest the absence of a quorum.

Bill Text

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Introduced in SenateIssued July 13, 2017

II

115th CONGRESS

1st Session

S. 1553

IN THE SENATE OF THE UNITED STATES

July 13, 2017

Mr. Johnson introduced the following bill; which was read twice and referred to the Committee on the Judiciary

A BILL

To amend the Controlled Substances Act to list fentanyl analogues as schedule I controlled substances.

1.

Short title

This Act may be cited as the Stopping Overdoses of Fentanyl Analogues Act.

2.

Fentanyl Analogues

Section 202(c) of the Controlled Substances Act (21 U.S.C. 812) is amended—

(a)

by adding at the end of subsection (b) of Schedule I the following:

(23)

Acetyl fentanyl 4-methylphenethyl.

(24)

Acrylfentanyl.

(25)

4-fluorobutyrylfentanyl.

(26)

4-fluoroisobutyryl fentanyl.

(27)

3-furanyl fentanyl.

(28)

Isobutyryl fentanyl.

(29)

Meta-fluorofentanyl.

(30)

Methoxyacetyl fentanyl.

(31)

4-methoxybutyrfentanyl.

(32)

Ocfentanil.

(33)

Ortho-fluorofentanyl.

(34)

Tetrahydrofuranyl fentanyl.

(35)

Valeryl fentanyl.

; and

(b)

by adding at the end of Schedule I the following:

(e)
(1)

Unless specifically exempted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of fentanyl analogues, or which contains their salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation.

(2)

In paragraph (1), the term fentanyl analogues includes any compound structurally derived from fentanyl—

(A)

by replacement of the phenyl portion of the phenethyl group by any monocycle, whether or not further substituted in or on the monocycle;

(B)

by substitution in or on the phenethyl group with alkyl, alkenyl, alkoxy, hydroxy, halo, haloalkyl, amino or nitro groups;

(C)

by substitution in or on the piperidine ring with alkyl, alkenyl, alkoxy, ester, ether, hydroxy, halo, haloalkyl, amino or nitro groups;

(D)

by replacement of the aniline ring with any aromatic monocycle whether or not further substituted in or on the aromatic monocycle; or

(E)

by replacement of the N-propionyl group by another acyl group.

.