S. 4984Senate117th Congress (2021-2023)In Committee

Zero Tolerance for Deceptive Fentanyl Trafficking Act

Sponsored by Tom CottonSen. Tom Cotton (R-AR)
Introduced September 28, 2022

AI-Generated Summary

Updated February 8, 2026 at 5:53 PM UTC

The Zero Tolerance for Deceptive Fentanyl Trafficking Act amends the Controlled Substances Act to make it a federal crime to knowingly misrepresent or market fentanyl, its analogues, or related substances as another drug. It imposes at least 20 years in prison and hefty fines, with life imprisonment or the death penalty for cases that cause death, involve intent to kill, prior felonies, or unlawful presence. The bill also adds several fentanyl‑related chemicals to Schedule I and expands the definition of “fentanyl‑related substance.” It targets anyone who sells or markets these substances, especially deceptive traffickers.

Key Provisions

  • Creates a new offense for knowingly misrepresenting or marketing fentanyl, fentanyl analogues, or fentanyl‑related substances as another drug.
  • Sets a minimum 20‑year prison term and fines; if the deception results in death or is intended to cause death, the penalty escalates to death or life imprisonment, and life imprisonment applies for offenders with prior felonies or who are unlawfully present in the U.S.
  • Adds specific fentanyl‑related substances (e.g., isobutyryl fentanyl, para‑methoxybutyrylfentanyl, valeryl fentanyl, cyclopentyl fentanyl, para‑chloroisobutyryl fentanyl) to Schedule I.
  • Broadly defines “fentanyl‑related substance” to cover many chemical modifications and lists additional examples such as 4′‑Methyl acetyl fentanyl, crotonyl fentanyl, and benzodioxole fentanyl.

Legislative Activity

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1 earlier action
SenateIntro Referral Latest Action

Read twice and referred to the Committee on the Judiciary.

September 28, 2022

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SenateIntro Referral

Introduced in Senate

September 28, 2022

SenateIntro Referral

Read twice and referred to the Committee on the Judiciary.

September 28, 2022

Floor Debate

9 members

What members said about S. 4984 on the floor

4 Republicans5 Democrats
Richard J. Durbin
Sen. Richard J. DurbinD-IL · Sep 28, 2022

Madam President, it has been a little more than 7 months since Russia launched its illegal invasion of Ukraine, and the destruction that has followed is unbelievable. We have all had a chance to bear…

Tom Cotton
Sen. Tom CottonR-AR · Sep 28, 2022

Madam President, the United States is in the midst of the deadliest drug epidemic in our Nation's history, caused by the most lethal drugs ever created. More than 108,000 Americans died last year…

Marsha Blackburn
Sen. Marsha BlackburnR-TN · Sep 28, 2022

Madam President, last evening, I had the opportunity to get on the phone in a telephone townhall with citizens from Davidson and Shelby Counties in Tennessee, and crime was the No. 1 issue that…

Tim Kaine
Sen. Tim KaineD-VA · Sep 28, 2022

Madam President, I was scheduled to come to the floor today to offer live UCs to bring up two Biden nominees--very important nominees--to assume diplomatic posts in the Western Hemisphere. Senator…

Roger Marshall
Sen. Roger MarshallR-KS · Sep 28, 2022

I ask unanimous consent that the order for the quorum call be rescinded. Madam President, I rise today in order to ask for unanimous consent to pass S.J. Res. 63, a resolution to terminate the…

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Catherine Cortez Masto
Sen. Catherine Cortez MastoD-NV · Sep 28, 2022

Madam President, 5 years ago this Saturday, my hometown of Las Vegas endured one of the darkest days in its history. On a beautiful autumn evening, the Route 91 Harvest Music Festival was interrupted…

Chuck Grassley
Sen. Chuck GrassleyR-IA · Sep 28, 2022

Madam President, as a leading advocate for lower drug prices in the Senate, No. 1, I have hauled Big Pharma and pharmacy benefit managers' executives before my committee of Congress; second, I led a…

Ron Wyden
Sen. Ron WydenD-OR · Sep 28, 2022

Reserving the right to object, Madam President. Madam President, I just went over to our colleague from Kansas and told him that I would much rather be on the floor this afternoon working in a…

Jon Ossoff
Sen. Jon OssoffD-GA · Sep 28, 2022

Mr. President, I ask unanimous consent that the order for the quorum call be rescinded.

Bill Text

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Introduced in SenateIssued September 28, 2022

II

117th CONGRESS

2d Session

S. 4984

IN THE SENATE OF THE UNITED STATES

September 28, 2022

Mr. Cotton (for himself, Mr. Cornyn, and Mr. Hawley) introduced the following bill; which was read twice and referred to the Committee on the Judiciary

A BILL

To amend the Controlled Substances Act to prohibit the deceptive sale of fentanyl, and for other purposes.

1.

Short title

This Act may be cited as the Zero Tolerance for Deceptive Fentanyl Trafficking Act.

2.

Prohibition of the deceptive sale of fentanyl

Section 401 of the Controlled Substances Act (21 U.S.C. 841) is amended by adding at the end the following:

(i)

Deceptive sale of fentanyl and fentanyl-Related substances

(1)

Offense

It shall be unlawful for any person to knowingly misrepresent or knowingly market as another substance a mixture or substance containing fentanyl, a fentanyl analogue, or a fentanyl-related substance (as defined in subsection (e)(2) of schedule I in section 202(c)).

(2)

Penalty

(A)

In general

Except as provided in subparagraph (B), any person who violates paragraph (1) shall be imprisoned for not less than 20 years and fined under title 18, United States Code.

(B)

Enhanced penalties

(i)

Death results

If a violation of paragraph (1) results in death or is committed with the intent to cause death, the person shall be sentenced to death or life imprisonment and fined under title 18, United States Code.

(ii)

Prior felony conviction or unlawful presence in the United States

A person who violates paragraph (1) shall be sentenced to life imprisonment and fined under title 18, United States Code, if the violation occurs—

(I)

after any other prior felony conviction of the person has become final; or

(II)

while the person is unlawfully present in the United States.

.

3.

Fentanyl-related substances

Schedule I in section 202(c) of the Controlled Substances Act (21 U.S.C. 812) is amended—

(1)

in subsection (b), by adding at the end the following:

(23)

Isobutyryl fentanyl.

(24)

Para-Methoxybutyrylfentanyl.

(25)

Valeryl fentanyl.

(26)

Cyclopentyl fentanyl.

(27)

Para-Chloroisobutyryl fentanyl.

; and

(2)

by adding at the end the following:

(e)
(1)

Unless specifically exempted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of a fentanyl-related substance, or which contains the salts, isomers, and salts of isomers of a fentanyl-related substance whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation.

(2)

For purposes of paragraph (1), the term fentanyl-related substance includes the following:

(A)

Any substance that is structurally related to fentanyl by one or more of the following modifications:

(i)

By replacement of the phenyl portion of the phenethyl group by any monocycle, whether or not further substituted in or on the monocycle.

(ii)

By substitution in or on the phenethyl group with alkyl, alkenyl, alkoxy, hydroxy, halo, haloalkyl, amino, or nitro groups.

(iii)

By substitution in or on the piperidine ring with alkyl, alkenyl, alkoxy, ester, ether, hydroxy, halo, haloalkyl, amino, or nitro groups.

(iv)

By replacement of the aniline ring with any aromatic monocycle whether or not further substituted in or on the aromatic monocycle.

(v)

By replacement of the N-propionyl group by another acyl group.

(B)

4′-Methyl acetyl fentanyl.

(C)

Crotonyl fentanyl.

(D)

2′-Fluoro ortho-fluorofentanyl.

(E)

Ortho-Methyl acetylfentanyl.

(F)

Thiofuranyl fentanyl.

(G)

Ortho-Fluorobutyryl fentanyl.

(H)

Ortho-Fluoroacryl fentanyl.

(I)

Beta-Methyl fentanyl.

(J)

Phenyl fentanyl.

(K)

Para-Methylfentanyl.

(L)

Beta′-Phenyl fentanyl.

(M)

Benzodioxole fentanyl.

.